N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide

Base Information

Chemical Name:N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide
CAS No.:786688-60-6
Molecular Formula:C₂₉H₂₀Cl₂FN₃O₄
Molecular Weight:564.4
Hs Code.:

Synonyms:N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide

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Chemical Property of N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide

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Technology Process of N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide

There total 1 articles about N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.1%

: 656237-85-3
N-(3,5-dichloropyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide

: 786688-60-6
N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide

Guidance literature:: N-(3,5-dichloropyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide; With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; acetic acid; at 20 ℃; for 168h;

With potassium carbonate; In dichloromethane; water; acetic acid; for 1h; pH=8;

Reference yield: 72.8%

: 786688-60-6
N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide

: N-(3,5-dichloro-1-oxopyridin-4-yl) [1-(4-fluorobenzyl)-5-hydroxyindol-3-yl]-glyoxylic acid amide

Guidance literature:: N-(3,5-dichloro-1-oxopyridin-4-yl) [5-benzyloxy-1-(4-fluorobenzyl)-indol-3-yl]-glyoxylic acid amide; With boron tribromide; In dichloromethane; for 3h; Heating / reflux;

With sodium hydrogencarbonate; In water; at 10 - 20 ℃; for 3h; pH=8 - 9;