3-Fluoro-5-(morpholin-4-yl)benzonitrile

Base Information

Chemical Name:3-Fluoro-5-(morpholin-4-yl)benzonitrile
CAS No.:220954-16-5
Molecular Formula:C₁₁H₁₁FN₂O
Molecular Weight:206.22
Hs Code.:
DSSTox Substance ID:DTXSID701284987
Nikkaji Number:J1.042.137C

Synonyms:3-fluoro-5-(morpholin-4-yl)benzonitrile;220954-16-5;3-fluoro-5-morpholin-4-ylbenzonitrile;3-fluoro-5-morpholinobenzonitrile;SCHEMBL594313;DTXSID701284987;3-fluoro-5-(4-morpholinyl)benzonitrile;3-(morpholin-4-yl)-5-fluoro-benzonitrile;EN300-252661

Suppliers and Price of 3-Fluoro-5-(morpholin-4-yl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 3-Fluoro-5-(morpholin-4-yl)benzonitrile

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:206.08554114
Heavy Atom Count:15
Complexity:257

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1C2=CC(=CC(=C2)C#N)F

Technology Process of 3-Fluoro-5-(morpholin-4-yl)benzonitrile

There total 2 articles about 3-Fluoro-5-(morpholin-4-yl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 110-91-8,99108-56-2
morpholine

: 64248-63-1
3,5-difluorobenzonitrile

: 220954-16-5
3-fluoro-5-morpholinobenzonitrile

Guidance literature:: In dimethyl sulfoxide; at 20 ℃;
DOI:10.1016/S0040-4039(01)00582-2

Reference yield: 78.0%

: 110-91-8,99108-56-2
morpholine

: 64248-63-1
3,5-difluorobenzonitrile

: 220954-16-5
3-fluoro-5-morpholinobenzonitrile

: 3,5-dimorpholinobenzonitrile

Guidance literature:: In dimethyl sulfoxide; at 100 ℃; for 60h;
DOI:10.1016/S0040-4039(98)02570-2

Reference yield: 88.0%

: 220954-16-5
3-fluoro-5-morpholinobenzonitrile

: 295311-40-9
3-fluoro-5-(4-morpholinyl)benzoic acid

Guidance literature:: 3-fluoro-5-morpholinobenzonitrile; With hydrogenchloride; water; at 100 ℃;

With sodium hydroxide; In water; at 0 ℃; pH=1 - 2; Product distribution / selectivity;