(1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate

Base Information

Chemical Name:(1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate
CAS No.:1352143-59-9
Molecular Formula:CHF₃O₃S*C₂₀H₂₄N₂
Molecular Weight:442.502
Hs Code.:

Synonyms:(1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate

Suppliers and Price of (1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate

There total 6 articles about (1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1493-13-6
trifluorormethanesulfonic acid

: (1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine

: 1352143-59-9
(1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate

Guidance literature:: In dichloromethane; at 20 ℃; for 1h;
DOI:10.1016/j.tet.2011.09.101

Reference yield:

: 1352143-58-8
C₂₈H₃₂N₄O₃

: 1352143-59-9
(1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol / 24 h / 50 °C

2: dichloromethane / 1 h / 20 °C

With potassium hydroxide; In ethanol; dichloromethane;
DOI:10.1016/j.tet.2011.09.101

Reference yield:

: 3594-90-9
2,2'-bis(hydroxymethyl)biphenyl

: 1352143-59-9
(1'R,2'R)-6-(2'-aminocyclohexyl)-6,7-dihydro-5H-dibenzo[c,e]azepine triflate

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen bromide; acetic acid / 0.5 h / Reflux

2: potassium carbonate / acetonitrile / 24 h / 60 °C

3: potassium hydroxide / ethanol / 24 h / 50 °C

4: dichloromethane / 1 h / 20 °C

With hydrogen bromide; potassium carbonate; acetic acid; potassium hydroxide; In ethanol; dichloromethane; acetonitrile;
DOI:10.1016/j.tet.2011.09.101