2-benzylthio-N₆-phenethyladenosine

Base Information

• Chemical Name: 2-benzylthio-N₆-phenethyladenosine
• CAS No.: 1379453-78-7
• Molecular Formula: C₂₅H₂₇N₅O₄S
• Molecular Weight: 493.586
• Mol file: 1379453-78-7.mol

Synonyms:2-benzylthio-N₆-phenethyladenosine

Chemical Property of 2-benzylthio-N₆-phenethyladenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzylthio-N₆-phenethyladenosine

There total 5 articles about 2-benzylthio-N₆-phenethyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C31H33N5O7S → 2-benzylthio-N6-phenethyladenosine (1379453-78-7)

Guidance literature:

With ethanol; sodium;

DOI:10.1016/j.ejmech.2012.03.047

Reference yield:

2-benzylthio-6-chloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine (1379453-58-3) → 2-benzylthio-N6-phenethyladenosine (1379453-78-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / ethanol / 12 h / Reflux

2: ethanol; sodium

With ethanol; sodium; triethylamine; In ethanol;

DOI:10.1016/j.ejmech.2012.03.047

Reference yield:

2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine (16321-99-6) → 2-benzylthio-N6-phenethyladenosine (1379453-78-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: acetonitrile / 0.5 h / 20 °C / Inert atmosphere

1.2: 6 h / 60 °C / Inert atmosphere

2.1: triethylamine / ethanol / 12 h / Reflux

3.1: ethanol; sodium

With ethanol; sodium; triethylamine; In ethanol; acetonitrile;

DOI:10.1016/j.ejmech.2012.03.047

upstream raw materials:

2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine

2-benzylthio-6-chloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine

G

2',3',5'-tri-O-acetyl-guanosine