2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester

Base Information

• Chemical Name: 2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester
• CAS No.: 37172-97-7
• Molecular Formula: C₂₅H₂₄O₆
• Molecular Weight: 420.462
• Mol file: 37172-97-7.mol

Synonyms:2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester

Chemical Property of 2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester

There total 4 articles about 2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methyl <3,5-dihydroxy-2-(methoxycarbonyl)phenyl>acetate (6110-30-1) + benzyl bromide (100-39-0) → 2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester (37172-97-7)

Guidance literature:

With sodium hydride;

DOI:10.1016/j.bmcl.2004.07.043

Reference yield: 91.0%

methyl <3,5-dihydroxy-2-(methoxycarbonyl)phenyl>acetate (6110-30-1) + benzyl alcohol (100-51-6,185532-71-2) → 2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester (37172-97-7)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ol2011117

Reference yield:

methyl <3,5-dihydroxy-2-(methoxycarbonyl)phenyl>acetate (6110-30-1) + benzyl bromide (100-39-0) → 2,4-bis-benzyloxy-6-methoxycarbonylmethylbenzoic acid methyl ester (37172-97-7) + dimethyl α-C-benzyl-3,5-dibenzyloxyhomophthalate (96864-16-3)

Guidance literature:

With potassium carbonate; In acetone; for 64h; Heating;

upstream raw materials:

methyl <3,5-dihydroxy-2-(methoxycarbonyl)phenyl>acetate

benzyl bromide

benzyl alcohol

Downstream raw materials:

2,4-bis-benzyloxy-6-carboxymethylbenzoic acid methyl ester

2,4-bis-benzyloxy-6-(2-oxopropyl)benzoic acid

2-(1-acetyl-2-(dimethylamino)vinyl)-4,6-bis-benzyloxybenzoic acid methyl ester

2-(7-hydroxy-1-oxooctyl)-3,5-dihydroxybenzeneacetic acid ethyl ester