methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Base Information

• Chemical Name: methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate
• CAS No.: 404369-26-2
• Molecular Formula: C₂₈H₂₈INO₄
• Molecular Weight: 569.439

Synonyms:methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Chemical Property of methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

There total 2 articles about methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate (302593-20-0) → methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate (404369-26-2)

Guidance literature:

With lithium iodide; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1016/S0040-4020(01)01070-5

Reference yield:

methyl 2-deoxy-3,4-O-isopropylidene-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate (302593-18-6) → methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate (404369-26-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / Et₃N / tetrahydrofuran / 0.25 h / 20 °C

2: 90 percent / LiI / dimethylformamide / 80 °C

With triethylamine; lithium iodide; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)01070-5

Reference yield: 90.0%

methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate (404369-26-2) → methyl (2R,3S)-3-hydroxy-2-[(9-phenyl-9-fluorenyl)-amino]-4-pentenoate (404369-27-3)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -40 ℃; for 0.333333h;

DOI:10.1016/S0040-4020(01)01070-5

upstream raw materials:

methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

methyl 2-deoxy-3,4-O-isopropylidene-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Downstream raw materials:

methyl (2R,3S)-3-hydroxy-2-[(9-phenyl-9-fluorenyl)-amino]-4-pentenoate

methyl (2R,3S)-3-(tert-butyldimethylsilyl)oxy-2-[(9-phenyl-9-fluorenyl)-amino]-4-pentenoate

cis-3-O-(tert-butyldimethylsilyl)-1-(9-phenyl-9-fluorenyl)-D-proline methyl ester

methyl (2R,3S)-3-(tert-butyldimethylsilyl)oxy-5-hydroxy-2-[(9-phenyl-9-fluorenyl)-amino]-pentanoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 404369-26-2 methyl 2-deoxy-3,4-O-isopropylidene-5-iodo-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Send

Send

Metric Ton KG G Pound L ML

Send

Send