TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER

Base Information

• Chemical Name: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER
• CAS No.: 10437-85-1
• Molecular Formula: C11H14 O3 S
• Molecular Weight: 226.296
• Hs Code.: 2906199090
• Mol file: 10437-85-1.mol

Synonyms:Cyclobutanol,4-methylbenzenesulfonate (9CI); Cyclobutanol, p-toluenesulfonate (7CI,8CI);Cyclobutyl 4-methylbenzenesulfonate; Cyclobutyl p-methylbenzenesulfonate;Cyclobutyl p-toluenesulfonate; Cyclobutyl tosylate; Tosyloxycyclobutane

Chemical Property of TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER

Chemical Property:

• PSA: 51.75000
• LogP: 3.33360

Purity/Quality:

98%,99%, ^*data from raw suppliers

TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER

There total 3 articles about TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

cyclobutanol (2919-23-5) + p-toluenesulfonyl chloride (98-59-9) → cyclobutyl 4-methylbenzenesulfonate (10437-85-1)

Guidance literature:

With pyridine; at 0 - 20 ℃; for 16.3333h;

DOI:10.15227/orgsyn.064.0050

Reference yield:

cyclobutanol (2919-23-5) → cyclobutyl 4-methylbenzenesulfonate (10437-85-1)

Guidance literature:

With diethyl ether; sodium hydride; und anschliessend mit TsCl;

DOI:10.1021/ja01155a005

Reference yield:

→ cyclobutyl 4-methylbenzenesulfonate (10437-85-1)

Guidance literature:

Verb. 2, p-TsCl;

DOI:10.1021/jo00862a013

upstream raw materials:

cyclobutanol

p-toluenesulfonyl chloride

Downstream raw materials:

cyclobutane thiol

1,5-dibromocyclopentene

(+/-)-2-bromocyclopent-2-enol

cyclobutene

Refernces

• 1、 Roberts,Chambers. "-". . p. 5034,5037. Retrieved 1951.
• 2、 -. "3-ARYL-2H-PYRAZOLO[4,3-b]PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS". Paragraph 0198; 0199. . Retrieved 2018/05/03.
• 3、 -. "COMPOUNDS HAVING CRTH2 ANTAGONIST ACTIVITY". Page/Page column 44. . Retrieved 2009/09/05.