1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride

Base Information

Chemical Name:1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride
CAS No.:70276-60-7
Molecular Formula:C₁₉H₁₉N₅O*ClH
Molecular Weight:369.854
Hs Code.:

Synonyms:1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride

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Chemical Property of 1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride

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Technology Process of 1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride

There total 4 articles about 1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

: 70276-51-6
1-Benzyl-5-(N-benzylformamido)-N'-ethoxy-1H-imidazole-4-carboxamidine

: 70276-60-7
1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; Raney Ni W-2; In water; for 9h; under 760 Torr; Ambient temperature;
DOI:10.1248/cpb.37.1504

Reference yield:

: 100-39-0
benzyl bromide

: 70276-60-7
1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / anhydrous K₂CO₃ / dimethylformamide / 5 h / Ambient temperature

2: 21 percent / H₂, 1N aqueous HCl / Raney Ni W-2 / H₂O / 9 h / 760 Torr / Ambient temperature

With hydrogenchloride; hydrogen; potassium carbonate; Raney Ni W-2; In water; N,N-dimethyl-formamide;
DOI:10.1248/cpb.37.1504

Reference yield:

: 70276-43-6,125661-60-1,125661-61-2
1-Benzyl-N'-ethoxy-5-formamido-1H-imidazole-4-carboxamidine

: 70276-60-7
1-Benzyl-5-(N-benzylformamido)-1H-imidazole-4-carboxamidine Hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / anhydrous K₂CO₃ / dimethylformamide / 5 h / Ambient temperature

2: 21 percent / H₂, 1N aqueous HCl / Raney Ni W-2 / H₂O / 9 h / 760 Torr / Ambient temperature

With hydrogenchloride; hydrogen; potassium carbonate; Raney Ni W-2; In water; N,N-dimethyl-formamide;
DOI:10.1248/cpb.37.1504