2-AMino-5-benzyloxy-4-Methoxybenzoic acid

Base Information Edit

Chemical Name:2-AMino-5-benzyloxy-4-Methoxybenzoic acid
CAS No.:909912-09-0
Molecular Formula:C₁₅H₁₅NO₄
Molecular Weight:273.288
Hs Code.:
Mol file:909912-09-0.mol

Synonyms:benzyl 2-amino-5-(benzyloxy)-4-methoxybenzoic acid

Suppliers and Price of 2-AMino-5-benzyloxy-4-Methoxybenzoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 2-AMino-5-benzyloxy-4-Methoxybenzoic acid Edit

Chemical Property:

Melting Point:108 °C(Solv: isopropanol (67-63-0))
Boiling Point:462.5±45.0 °C(Predicted)
PKA:2.32±0.10(Predicted)
Density:1.283±0.06 g/cm3(Predicted)

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-AMino-5-benzyloxy-4-Methoxybenzoic acid

There total 10 articles about 2-AMino-5-benzyloxy-4-Methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 855793-63-4
methyl 2-amino-5-(benzyloxy)-4-methoxybenzoate

: 909912-09-0
benzyl 2-amino-5-(benzyloxy)-4-methoxybenzoic acid

Guidance literature:: methyl 2-amino-5-(benzyloxy)-4-methoxybenzoate; With lithium hydroxide; water; In tetrahydrofuran; methanol; at 75 ℃; for 6h;

With hydrogenchloride; In water; pH=6 - 7;

Reference yield: 89.0%

: 634197-80-1
2-amino-5-benzyloxy-4-methoxybenzoic acid benzyl ester

: 909912-09-0
benzyl 2-amino-5-(benzyloxy)-4-methoxybenzoic acid

Guidance literature:: With methanol; lithium hydroxide; for 18h; Inert atmosphere;

Reference yield:

: 164161-49-3
methyl 5-(benzyloxy)-4-methoxy-2-nitrobenzoate

: 909912-09-0
benzyl 2-amino-5-(benzyloxy)-4-methoxybenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: iron; ammonium chloride / methanol; water / 24 h / 90 °C

2.1: lithium hydroxide / tetrahydrofuran; methanol; water / 6 h / 75 °C

2.2: pH 7

With iron; ammonium chloride; lithium hydroxide; In tetrahydrofuran; methanol; water;
DOI:10.1021/jm2001508