3,3'-Bipyridazine

Base Information

• Chemical Name: 3,3'-Bipyridazine
• CAS No.: 10198-96-6
• Molecular Formula: C8H6 N4
• Molecular Weight: 158.16
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID20499290
• Nikkaji Number: J502.910D
• Mol file: 10198-96-6.mol

Synonyms:3,3'-Bipyridazine;10198-96-6;3-pyridazin-3-ylpyridazine;3,3/'-BIPYRAZINE;3,3'-BIPYRAZINE;bidiazine;3,3-BIPYRAZINE;3-(pyridazin-3-yl)pyridazine;SCHEMBL1456807;DTXSID20499290;EN300-139163

Chemical Property of 3,3'-Bipyridazine

Chemical Property:

• PSA: 51.56000
• LogP: 0.93360
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 158.059246208
• Heavy Atom Count: 12
• Complexity: 123

Purity/Quality:

97% ^*data from raw suppliers

3,3'-BIPYRAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NN=C1)C2=NN=CC=C2

Technology Process of 3,3'-Bipyridazine

There total 3 articles about 3,3'-Bipyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2H-Pyridazin-3-one (504-30-3) → 3,3'-bipyridazine (10198-96-6)

Guidance literature:

2H-Pyridazin-3-one; With triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In 1,4-dioxane; at 100 ℃; for 0.5h; Inert atmosphere; Sealed vessel; Microwave irradiation;

With copper(l) iodide; palladium diacetate; potassium carbonate; triphenylphosphine; In 1,4-dioxane; 2,4-dichlorophenoxyacetic acid dimethylamine; at 120 ℃; for 0.666667h; Inert atmosphere; Microwave irradiation; Sealed vessel;

DOI:10.1021/ol300455e

Reference yield: 2.0%

1,2-diazine (289-80-5) → 3,3'-bipyridazine (10198-96-6)

Guidance literature:

With palladium 10% on activated carbon; for 26h; Reflux; Inert atmosphere;

DOI:10.1055/s-0041-1737792

Reference yield:

→ 3,3'-bipyridazine (10198-96-6)

Guidance literature:

3-halogene-(Cl,Br)pyridazine(Ia),Pd-CaCO3,5percent KOH/MeOH or NaOH/EtOH,80percent N2H4*H2O;

upstream raw materials:

1,2-diazine

2H-Pyridazin-3-one

Downstream raw materials:

(3,3'-bipyridazine)bis(triphenylphosphine)copper(I) tetrafluoroborate