N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide

Base Information

Chemical Name:N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide
CAS No.:120449-76-5
Molecular Formula:C₁₈H₁₄Br₂N₄O₂
Molecular Weight:478.143
Hs Code.:

Synonyms:N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide

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Chemical Property of N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide

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Technology Process of N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide

There total 2 articles about N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 100-52-7
benzaldehyde

: 40889-54-1
6,8-dibromo-2-methyl-4-oxo-3-quinazolineacetic acid hydrazide

: 120449-76-5
N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide

Guidance literature:: With acetic acid; In ethanol; for 10h; Reflux;
DOI:10.1016/j.ejmech.2021.113609

Reference yield:

: 40889-53-0
(6,8-dibromo-2-methyl-4-oxo-4H-quinazolin-3-yl)-acetic acid ethyl ester

: 120449-76-5
N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / ethanol / 12 h / Reflux

2: acetic acid / ethanol / 10 h / Reflux

With acetic acid; hydrazine; In ethanol;
DOI:10.1016/j.ejmech.2021.113609