dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

Chemical Name:dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
CAS No.:96575-49-4
Molecular Formula:C₁₈H₁₉NO₅
Molecular Weight:329.353
Hs Code.:

Synonyms:dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Suppliers and Price of dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

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Technology Process of dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

There total 3 articles about dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 96557-29-8
dimethyl 2,6-dimethyl-4-<2-(2-(1,3-dioxolanyl))phenyl>-1,4-dihydropyridine-3,5-dicarboxylate

: 96575-49-4
dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Guidance literature:: With toluene-4-sulfonic acid; In acetone; for 24h; Ambient temperature;
DOI:10.1021/jo00214a004

Reference yield:

: 34824-58-3
2-(2-bromophenyl)-1,3-dioxolan

: 96575-49-4
dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) n-buthyllithium / 1.) THF, hexane, -78 deg C, 0.5 h, 2.) THF, hexane,from -78 deg C to RT, 6 h

2: 57 percent / aq. NH₃ / methanol / 24 h / Heating

3: 93 percent / p-toluenosulfonic acid monohydrate / acetone / 24 h / Ambient temperature

With ammonium hydroxide; n-butyllithium; toluene-4-sulfonic acid; In methanol; acetone;
DOI:10.1021/jo00214a004

Reference yield:

: 59259-01-7
2-<2-(1,3-dioxolanyl)>benzaldehyde

: 96575-49-4
dimethyl 2,6-dimethyl-4-(2-formylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / aq. NH₃ / methanol / 24 h / Heating

2: 93 percent / p-toluenosulfonic acid monohydrate / acetone / 24 h / Ambient temperature

With ammonium hydroxide; toluene-4-sulfonic acid; In methanol; acetone;
DOI:10.1021/jo00214a004