34824-58-3

Usage

Uses

Used in Organic Synthesis:
2-(2-BROMOPHENYL)-1,3-DIOXOLANE is used as a key intermediate for the synthesis of a wide range of organic compounds. Its unique structure allows for versatile reactions, making it a valuable component in the creation of new molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-(2-BROMOPHENYL)-1,3-DIOXOLANE is utilized as a vital building block for the development of various drugs. Its incorporation into drug molecules can enhance their efficacy and pharmacological properties, contributing to the advancement of novel therapeutic agents.
Used in Agrochemicals:
2-(2-BROMOPHENYL)-1,3-DIOXOLANE is employed as a raw material in the agrochemical industry, where it is used to produce compounds with pesticidal, herbicidal, and fungicidal properties. Its role in the synthesis of these agrochemicals helps to improve crop protection and yield.
Used in Dye Industry:
In the dyestuffs industry, 2-(2-BROMOPHENYL)-1,3-DIOXOLANE is used as an essential raw material for the production of various dyes. Its chemical properties enable the creation of dyes with specific color characteristics and improved performance, catering to the diverse needs of the textile and other related industries.

InChI:InChI=1/C9H9BrO2/c10-8-4-2-1-3-7(8)9-11-5-6-12-9/h1-4,9H,5-6H2

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 107-07-3 2-chloro-ethanol 
• 7732-18-5 water 
• 144-55-8 sodium hydrogencarbonate 
• 7381-30-8 2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 95-46-5 2-methylphenyl bromide 
• 107-21-1 ethylene glycol 

Downstream Products

• 90320-65-3 Ethyl 2-<2-(1,3-dioxolan-2-yl)phenylacetate> 
• 142483-70-3 2-<2'-(4''-bromobutyl)>phenyl-1,3-dioxolane 
• 59259-01-7 2-<2-(1,3-dioxolanyl)>benzaldehyde 
• 128563-80-4 8-<2-(1,3-Dioxolan-2-yl)phenyl>-1,4-dioxaspiro<4.5>decan-8-ol 
• 156574-96-8 4,4-dimethyl-2-<2-(2-<1,3-dioxolan-2-yl>phenyl)phenyl>oxazoline 
• 131985-28-9 8-<2-(1,3-Dioxolan-2-yl)phenyl>-7-methyl-1,4-dioxaspiro<4.5>decan-8-ol 
• 156424-40-7 (2,5-Bis-methoxymethoxy-phenyl)-(2-[1,3]dioxolan-2-yl-phenyl)-methanol 
• 1210-05-5 Biphenyl-2,2'-dicarbaldehyde 
• 150711-15-2 2-(2-pyridylphenyl)-1,3-dioxolane 
• 62708-42-3 o-allylbenzaldehyde 
• 96689-74-6 2-(2-propenyl)benzaldehyde ethylene glycol acetal 
• 175235-44-6 Cyclopentyl-(2-[1,3]dioxolan-2-yl-phenyl)-methanone 
• 175235-46-8 (2-[1,3]Dioxolan-2-yl-phenyl)-(7-methoxy-indan-1-yl)-methanone 
• 106569-07-7 2,2'-<1,1'-biphenyl>-2,2'-diylbis(1,3-dioxolane) 

Relevant academic research and scientific papers

Conformational diastereoisomerism in tris-( 2-alkylimino) triphenylphosphines

A combination of one-dimensional, two-dimensional and nuclear Overhauser experiments allow complete NMR spectroscopic characterisation of the trifunctionalised triphenylphosphine, tris-(2-carboxaldehyde)triphenylphosphine 1. A single-crystal X-ray diffrac

Phosphine-Catalyzed Intramolecular Vinylogous Aldol Reaction of α-Substituted Enones

We demonstrate the first phosphine-catalyzed intramolecular vinylogous aldol reaction (IVAR) of α-substituted enones. This strategy provides access to various pentannulated (hetero)arenes and dibenzocycloheptanones incorporated with two contiguous stereocenters, one of which is an all-carbon quaternary center. The scope of this work is further broadened through elaborations of the IVAR adducts to (i) benzannulated nine-membered carbocyclic systems, (ii) interesting classes of 1,3-dienes, 1,3,5-trienes, and 1-yn-3,5-dienes, and (iii) the analogs of echinolactone D and russujaponol F.

Cobalt-Catalyzed Chemoselective Transfer Hydrogenative Cyclization Cascade of Enone-Tethered Aldehydes

The ligand-free Co-catalyzed chemoselective reductive cyclization cascade of enone-tethered aldehydes with i-PrOH as the environmentally benign hydrogen surrogate is developed by this study. Mechanistic studies disclosed that such a protocol is initiated

Copper-Catalyzed Tandem Cross-Coupling and Alkynylogous Aldol Reaction: Access to Chiral Exocyclic α-Allenols

An enantioselective copper-catalyzed tandem cross-coupling/alkynylogous aldol reaction has been developed. The tetrasubstituted allenoates containing both central and axial chirality have been obtained in moderate to good yields and excellent enantio-and

Annulative Morita-Baylis-Hillman reaction to synthesise chiral dibenzocycloheptanes

We describe the first metal-free and organocatalytic strategy to access highly functionalised dibenzocycloheptanesviaa phosphine-promoted annulative Morita-Baylis-Hillman (MBH) reaction. The method is manipulated to access to chiral dibenzocycloheptanes as well. This work represents a rare entry for the construction of seven-membered carbocyclesviathe MBH route. The realisation of several bioactive molecules possessing the dibenzocycloheptane core makes this an attractive strategy.

Rigid four-nitrogen four-tooth fourth subgroup metal complex and application thereof

The invention provides a rigid tetra-nitrogen four-tooth fourth subgroup metal complex, which has the structure shown in the formula (I): wherein n is 2 - 4. R Is C1 - C30 alkyl, C6 - C30 aryl or substituted aryl of C6 - C30. X Is a halogen, C1 - C30 alky

Catalytic Synthesis of 8-Membered Ring Compounds via Cobalt(III)-Carbene Radicals

The metalloradical activation of o-aryl aldehydes with tosylhydrazide and a cobalt(II) porphyrin catalyst produces cobalt(III)-carbene radical intermediates, providing a new and powerful strategy for the synthesis of medium-sized ring structures. Herein we make use of the intrinsic radical-type reactivity of cobalt(III)-carbene radical intermediates in the [CoII(TPP)]-catalyzed (TPP=tetraphenylporphyrin) synthesis of two types of 8-membered ring compounds; novel dibenzocyclooctenes and unprecedented monobenzocyclooctadienes. The method was successfully applied to afford a variety of 8-membered ring compounds in good yields and with excellent substituent tolerance. Density functional theory (DFT) calculations and experimental results suggest that the reactions proceed via hydrogen atom transfer from the bis-allylic/benzallylic C?H bond to the carbene radical, followed by two divergent processes for ring-closure to the two different types of 8-membered ring products. While the dibenzocyclooctenes are most likely formed by dissociation of o-quinodimethanes (o-QDMs) which undergo a non-catalyzed 8π-cyclization, DFT calculations suggest that ring-closure to the monobenzocyclooctadienes involves a radical-rebound step in the coordination sphere of cobalt. The latter mechanism implies that unprecedented enantioselective ring-closure reactions to chiral monobenzocyclooctadienes should be possible, as was confirmed for reactions mediated by a chiral cobalt-porphyrin catalyst.

Efficient synthesis of dibenzazepine lactams via a sequential Pd-catalyzed amination and aldol condensation reaction

A simple and efficient reaction was developed for the synthesis of dibenzazepine lactam derivatives. The core 7-membered azepine ring was formed by a stepwise sequence involving a palladium-catalyzed amination and an aldol condensation.

Enantioselective Synthesis of Isoxazolines Enabled by Palladium-Catalyzed Carboetherification of Alkenyl Oximes

Reported here is a highly efficient Pd/Xiang-Phos catalyzed enantioselective carboetherification of alkenyl oximes with either aryl or alkenyl halides, delivering various chiral 3,5-disubstituted and 3,5,5-trisubstituted isoxazolines in good yields with u

Structural Dynamics and Stereoselectivity of Chiral Benzylideneamine N,C-Chelate Borane Photo–Thermal Isomerization

New chiral N,C-chelate organoboron compounds based on benzylideneamines (bza) with the general formula of B(bza-R)Mes2 (R=H or Me; Mes=mesityl) are reported. A chiral substituent group R- or S-CH(CH3)Ph (Ph=phenyl) was introduced to