C₂₂H₂₈N₂O₃

Base Information

• Chemical Name: C₂₂H₂₈N₂O₃
• CAS No.: 1318779-96-2
• Molecular Formula: C₂₂H₂₈N₂O₃
• Molecular Weight: 368.476
• Mol file: 1318779-96-2.mol

Synonyms:C₂₂H₂₈N₂O₃

Chemical Property of C₂₂H₂₈N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₈N₂O₃

There total 6 articles about C₂₂H₂₈N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H26N2O5 (1318779-87-1) → C22H28N2O3 (1318779-96-2)

Guidance literature:

With 14% Pd/C; hydrogen; In dichloromethane; at 20 ℃;

DOI:10.1021/ol2018455

Reference yield:

C15H20ClNO4 (1318779-88-2) → C22H28N2O3 (1318779-96-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: ammonium hydroxide

2.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C

2.2: 0.08 h / 20 °C

3.1: 14% Pd/C; hydrogen / dichloromethane / 20 °C

With ammonium hydroxide; 14% Pd/C; hydrogen; sodium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ol2018455

Reference yield:

2-((2-ethylhexyl)oxy)-5-nitrobenzoic acid (1039902-87-8) → C22H28N2O3 (1318779-96-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1.5 h / 20 °C / Reflux

2.1: ammonium hydroxide

3.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C

3.2: 0.08 h / 20 °C

4.1: 14% Pd/C; hydrogen / dichloromethane / 20 °C

With ammonium hydroxide; oxalyl dichloride; 14% Pd/C; hydrogen; sodium hydride; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ol2018455

upstream raw materials:

2-((2-ethylhexyl)oxy)-5-nitrobenzoic acid

C₁₅H₂₀ClNO₄

C₁₅H₂₂N₂O₄

C₂₂H₂₆N₂O₅

Downstream raw materials:

C₃₀H₃₂F₃N₃O₄