methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate

Base Information

• Chemical Name: methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate
• CAS No.: 1429347-62-5
• Molecular Formula: C₂₀H₂₄BrNO₄S
• Molecular Weight: 454.385
• Mol file: 1429347-62-5.mol

Synonyms:methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate

Chemical Property of methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate

There total 2 articles about methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2-bromo-5-(chlorosulfonyl)benzoate (924867-87-8) + 4-ethyl-N-(2-methylpropyl)aniline → methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate (1429347-62-5)

Guidance literature:

With pyridine; at 20 ℃; for 17h;

Reference yield:

4-aminoethylbenzene (589-16-2) → methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate (1429347-62-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium iodide; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)] / water / 1.5 h / 150 °C / Microwave irradiation

2: pyridine / 17 h / 20 °C

With pyridine; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; potassium iodide; In water;

Reference yield:

methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate (1429347-62-5) → 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoic acid (1429347-18-1)

Guidance literature:

methyl 2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoate; With -butyl vinyl ether; palladium diacetate; triethylamine; triphenylphosphine; In acetonitrile; at 150 ℃; for 1h; Microwave irradiation;

With hydrogenchloride; In tetrahydrofuran; water; for 1h;

upstream raw materials:

4-aminoethylbenzene

methyl 2-bromo-5-(chlorosulfonyl)benzoate

Downstream raw materials:

2-bromo-5-(N-(4-ethylphenyl)-N-isobutylsulfamoyl)benzoic acid