benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate

Base Information

Chemical Name:benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate
CAS No.:1246458-52-5
Molecular Formula:C₃₉H₄₄FN₃O₅
Molecular Weight:653.794
Hs Code.:

Synonyms:benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate

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Chemical Property of benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate

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Technology Process of benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate

There total 1 articles about benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-44-5
phosgene

: 639862-23-0
4-(4-fluorobenzylamino)-piperidine-1-carboxylic acid benzyl ester

: 1246458-51-4
(4-(3-benzyloxy-2-methylpropoxy)phenyl)methanamine

: 1246458-52-5
benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate

Guidance literature:: (4-(3-benzyloxy-2-methylpropoxy)phenyl)methanamine; With sodium carbonate; In dichloromethane; water; at 0 ℃;

phosgene; In dichloromethane; water; toluene; at 0 ℃; for 1h;

4-(4-fluorobenzylamino)-piperidine-1-carboxylic acid benzyl ester; In dichloromethane; at 20 ℃;

Reference yield:

: 1246458-52-5
benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate

: 1246458-26-3
1-(4-fluorobenzyl)-3-(4-(3-hydroxy-2-methylpropoxy)benzyl)-1-(piperidin-4-yl)urea

Guidance literature:: benzyl 4-(3-(4-(3-(benzyloxy)-2-methylpropoxy)benzyl)-1-(4-fluorobenzyl)ureido)piperidine-1-carboxylate; With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In methanol; water; ethyl acetate; for 2h; under 760.051 Torr;

With triethylamine; In methanol; water; ethyl acetate;