5--1,2,3-trimethoxybenzene

Base Information

• Chemical Name: 5--1,2,3-trimethoxybenzene
• CAS No.: 120040-61-1
• Molecular Formula: C₂₂H₂₂O₃S₂
• Molecular Weight: 398.547
• Mol file: 120040-61-1.mol

Synonyms:5--1,2,3-trimethoxybenzene

Chemical Property of 5--1,2,3-trimethoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5--1,2,3-trimethoxybenzene

There total 3 articles about 5--1,2,3-trimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3,4,5-trimethoxy-benzaldehyde (86-81-7) + diphenyldisulfane (882-33-7) → 5--1,2,3-trimethoxybenzene (120040-61-1)

Guidance literature:

With tributylphosphine; In benzene; for 2.5h;

DOI:10.1021/jo00301a026

Reference yield: 42.0%

3,4,5-trimethoxy-benzaldehyde (86-81-7) + thiophenol (108-98-5) → 5--1,2,3-trimethoxybenzene (120040-61-1)

Guidance literature:

With trifluoroacetic acid; In chloroform; at 20 ℃; for 20h;

DOI:10.1002/chem.201600208

Reference yield: 29.0%

(3,4,5-trimethoxyphenyl)methanol (3840-31-1) + thiophenol (108-98-5) → 5--1,2,3-trimethoxybenzene (120040-61-1) + 3,4,5-trimethoxybenzyl phenyl sulfide (123731-52-2)

Guidance literature:

With oxygen; 9-(2-mesityl)-10-methylacridinium perchlorate; In acetonitrile; at 30 - 35 ℃; for 24h; Schlenk technique; Irradiation;

DOI:10.1039/d0cc02352c

upstream raw materials:

3,4,5-trimethoxy-benzaldehyde

diphenyldisulfane

thiophenol

(3,4,5-trimethoxyphenyl)methanol

Downstream raw materials:

(+)-trans-burseran

(-)-(3R,4R)-3-(3,4-methylenedioxybenzyl)-4-(3,4,5-trimethoxybenzyl)tetrahydrofuran

2''-Chloroburseran

Benzo[1,3]dioxol-5-yl-[(3R,4R,5S)-5-benzyloxy-4-(3,4,5-trimethoxy-benzyl)-tetrahydro-furan-3-yl]-methanone