1-Trifluoromethyl-4-(2-methyl-1-propenyl)benzene

Base Information

Chemical Name:1-Trifluoromethyl-4-(2-methyl-1-propenyl)benzene
CAS No.:115665-60-6
Molecular Formula:C₁₁H₁₁F₃
Molecular Weight:200.204
Hs Code.:
DSSTox Substance ID:DTXSID401215589
Nikkaji Number:J1.534.377J

Synonyms:1-trifluoromethyl-4-(2-methyl-1-propenyl)benzene;115665-60-6;SCHEMBL18026783;OYRLSUFNVRNZSW-UHFFFAOYSA-N;DTXSID401215589;1-(2-Methyl-1-propen-1-yl)-4-(trifluoromethyl)benzene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Trifluoromethyl-4-(2-methyl-1-propenyl)benzene

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:200.08128484
Heavy Atom Count:14
Complexity:203

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=CC1=CC=C(C=C1)C(F)(F)F)C

Technology Process of 1-Trifluoromethyl-4-(2-methyl-1-propenyl)benzene

There total 3 articles about 1-Trifluoromethyl-4-(2-methyl-1-propenyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 24470-78-8
isopropyltriphenylphosphonium iodide

: 115665-60-6
1-trifluoromethyl-4-(2-methyl-1-propenyl)benzene

Guidance literature:: isopropyltriphenylphosphonium iodide; With n-butyllithium; In tetrahydrofuran; at 0 - 20 ℃; for 4h; Inert atmosphere;

4-Trifluoromethylbenzaldehyde; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/jacs.1c03872

Reference yield:

: 864878-71-7
2-methyl-1-(4-(trifluoromethyl)phenyl)propan-2-ol

: 115665-60-6
1-trifluoromethyl-4-(2-methyl-1-propenyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 21 h / 20 °C / Inert atmosphere

2.1: potassium tert-butylate / 1 h / 20 °C / Sealed tube; Inert atmosphere

With potassium tert-butylate; sodium hydride; In tetrahydrofuran;
DOI:10.1002/ejoc.202100597