N-(2,4-dimethylphenyl)-N-methylmethacrylamide

Base Information

• Chemical Name: N-(2,4-dimethylphenyl)-N-methylmethacrylamide
• CAS No.: 1382847-03-1
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.284
• Mol file: 1382847-03-1.mol

Synonyms:N-(2,4-dimethylphenyl)-N-methylmethacrylamide

Chemical Property of N-(2,4-dimethylphenyl)-N-methylmethacrylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2,4-dimethylphenyl)-N-methylmethacrylamide

There total 2 articles about N-(2,4-dimethylphenyl)-N-methylmethacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2,4-dimethylphenyl)methacrylamide (29639-60-9) + methyl iodide (74-88-4) → N-(2,4-dimethylphenyl)-N-methylmethacrylamide (1382847-03-1)

Guidance literature:

methacrylic acid-(2,4-dimethyl-anilide); With sodium hydride; In tetrahydrofuran; at 0 ℃;

methyl iodide; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1016/j.tetlet.2017.12.053 DOI:10.1055/s-0037-1611781

Reference yield:

2,4-Xylidine (95-68-1) → N-(2,4-dimethylphenyl)-N-methylmethacrylamide (1382847-03-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 0 - 20 °C

2.1: sodium hydride / tetrahydrofuran / 0 °C

2.2: 0 - 20 °C

With sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.tetlet.2017.12.053

Reference yield: 67.0%

1-phenylcyclopropan-1-ol (29526-96-3) + N-(2,4-dimethylphenyl)-N-methylmethacrylamide (1382847-03-1) → C22H25NO2

Guidance literature:

With sodium persulfate; acetic acid; In water; at 50 ℃; Inert atmosphere;

DOI:10.1039/c6ra03431d

upstream raw materials:

2,4-Xylidine

N-(2,4-dimethylphenyl)methacrylamide

methyl iodide