4-(4-Fluorophenoxy)phenol

Base Information

• Chemical Name: 4-(4-Fluorophenoxy)phenol
• CAS No.: 1524-19-2
• Molecular Formula: C12H9 F O2
• Molecular Weight: 204.201
• Hs Code.: 2909500000
• European Community (EC) Number: 627-188-2
• DSSTox Substance ID: DTXSID00513524
• Nikkaji Number: J1.297.478G
• Wikidata: Q82373381
• Mol file: 1524-19-2.mol

Synonyms:4-(4-FLUOROPHENOXY)PHENOL;1524-19-2;4-(4-Fluoro-phenoxy)-phenol;p-(p-fluorophenoxy)phenol;4-(4-fluorophenoxy) phenol;SCHEMBL522433;DTXSID00513524;KIVFDFJTCRMULF-UHFFFAOYSA-N;4-(4-Fluorophenoxy)phenol, 97%;AMY41472;MFCD00792448;AKOS002679552;BS-23170;CS-0447279;EN300-124879;J-008919

Chemical Property of 4-(4-Fluorophenoxy)phenol

Chemical Property:

• Melting Point: 94-98 °C
• Boiling Point: 311.0±27.0 °C(Predicted)
• PKA: 10.07±0.26(Predicted)
• PSA: 29.46000
• Density: 1 +-.0.06 g/cm3(Predicted)
• LogP: 3.32360
• Storage Temp.: 2-8°C
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 204.05865769
• Heavy Atom Count: 15
• Complexity: 182

Purity/Quality:

99% ^*data from raw suppliers

4-(4-Fluorophenoxy)phenol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn,N
• Statements: 22-37/38-41-51/53
• Safety Statements: 26-39-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1O)OC2=CC=C(C=C2)F

Technology Process of 4-(4-Fluorophenoxy)phenol

There total 11 articles about 4-(4-Fluorophenoxy)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ 4-(4-fluorophenoxy)phenol (1524-19-2)

Guidance literature:

With methanol; copper(II) ferrite; at 20 ℃; for 24h;

Reference yield: 92.0%

C19H15FO2 → 4-(4-fluorophenoxy)phenol (1524-19-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; at 20 ℃;

DOI:10.1016/j.bmcl.2007.07.012

Reference yield: 72.9%

1-fluoro-4-(4-methoxyphenoxy)benzene (26129-34-0) → 4-(4-fluorophenoxy)phenol (1524-19-2)

Guidance literature:

With hydrogen bromide; acetic acid; for 16h; Inert atmosphere; Schlenk technique; Reflux;

DOI:10.1039/c3ra46392c

upstream raw materials:

4-(4-fluorophenoxy)benzaldehyde

4-fluoro-1-iodobenzene

hydroquinone

4-Fluorophenol

Downstream raw materials:

2-[4-(4-Fluoro-phenoxy)-phenoxy]-butyric acid

2-hydroxy-5-(4-fluorophenoxy)benzaldehyde

3-bromopropyl 2-chloro-4-(4-fluorophenoxy)phenyl ether

1-(4-(3-chloropropoxy)phenoxy)-4-fluorobenzene