2,4,5-TRIFLUORO-6-BROMOANILINE

Base Information

• Chemical Name: 2,4,5-TRIFLUORO-6-BROMOANILINE
• CAS No.: 1481-21-6
• Molecular Formula: C₆H₃BrF₃N
• Molecular Weight: 225.996
• Hs Code.: 2921420090
• Mol file: 1481-21-6.mol

Synonyms:Aniline,2-bromo-3,4,6-trifluoro- (7CI,8CI)

Chemical Property of 2,4,5-TRIFLUORO-6-BROMOANILINE

Chemical Property:

• Vapor Pressure: 0.176mmHg at 25°C
• Melting Point: 42-44 °C(lit.)
• Refractive Index: 1.545
• Boiling Point: 212.2°Cat760mmHg
• PKA: 0.19±0.10(Predicted)
• Flash Point: 97.2°C
• PSA: 26.02000
• Density: 1.875g/cm³
• LogP: 3.02980
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-3,4,6-trifluoroaniline ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4,5-TRIFLUORO-6-BROMOANILINE

There total 1 articles about 2,4,5-TRIFLUORO-6-BROMOANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-bromo-3,4,6-trifluoroaniline (1481-21-6)

Guidance literature:

Aus 2,4,5-Trifluor-anilin, Brom in Eg. (Fe, NaAc);

Reference yield:

2-bromo-3,4,6-trifluoroaniline (1481-21-6) + allyltributylstanane (24850-33-7) → C9H8F3N

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 80 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.02.022

Reference yield:

2-bromo-3,4,6-trifluoroaniline (1481-21-6) → cis-bis(2-bromo-5H-3,4,6-trifluorophenyl)diazene + trans-bis(2-bromo-5H-3,4,6-trifluorophenyl)diazene

Guidance literature:

With manganese(IV) oxide; In Petroleum ether; Overall yield = 31.8 %; Overall yield = 95 mg;

DOI:10.1039/c5cc08590j