N¹,N⁴-bis(mesitylenesulfonyl)-N¹-(tert-butoxycarbonyl)-N⁴-ethyl-1,4-diaminobutane

Base Information

• Chemical Name: N¹,N⁴-bis(mesitylenesulfonyl)-N¹-(tert-butoxycarbonyl)-N⁴-ethyl-1,4-diaminobutane
• CAS No.: 189341-49-9
• Molecular Formula: C₂₉H₄₄N₂O₆S₂
• Molecular Weight: 580.81
• Mol file: 189341-49-9.mol

Synonyms:N¹,N⁴-bis(mesitylenesulfonyl)-N¹-(tert-butoxycarbonyl)-N⁴-ethyl-1,4-diaminobutane

Chemical Property of N¹,N⁴-bis(mesitylenesulfonyl)-N¹-(tert-butoxycarbonyl)-N⁴-ethyl-1,4-diaminobutane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹,N⁴-bis(mesitylenesulfonyl)-N¹-(tert-butoxycarbonyl)-N⁴-ethyl-1,4-diaminobutane

There total 1 articles about N¹,N⁴-bis(mesitylenesulfonyl)-N¹-(tert-butoxycarbonyl)-N⁴-ethyl-1,4-diaminobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,4,6-trimethylbenzenesulfonyl)carbamic acid tert-butyl ester (56830-76-3) + N-(4-bromobutyl)-N-ethylmesitylenesulfonamide (161452-15-9) → N1,N4-bis(mesitylenesulfonyl)-N1-(tert-butoxycarbonyl)-N4-ethyl-1,4-diaminobutane (189341-49-9)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 0 deg C, 40 min, 2.) DMF, 60 deg C, 18 h;

DOI:10.1021/jm960849j

Reference yield: 100.0%

N1,N4-bis(mesitylenesulfonyl)-N1-(tert-butoxycarbonyl)-N4-ethyl-1,4-diaminobutane (189341-49-9) → N1,N4-bis(mesitylenesulfonyl)-N4-ethyl-1,4-diaminobutane (189341-51-3)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 0.833333h;

DOI:10.1021/jm960849j

Reference yield:

N1,N4-bis(mesitylenesulfonyl)-N1-(tert-butoxycarbonyl)-N4-ethyl-1,4-diaminobutane (189341-49-9) → 3,8,14-Tris(mesitylenesulfonyl)-3,8,14-Triazahexadecane (189341-53-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / trifluoroacetic acid / CH₂Cl₂ / 0.83 h / 0 - 20 °C

2: 1.) NaH / 1.) DMF, 0 deg C, 30 min, 2.) DMF, 89 deg C, overnight

With sodium hydride; trifluoroacetic acid; In dichloromethane;

DOI:10.1021/jm960849j

upstream raw materials:

(2,4,6-trimethylbenzenesulfonyl)carbamic acid tert-butyl ester

N-(4-bromobutyl)-N-ethylmesitylenesulfonamide

Downstream raw materials:

N¹,N⁴-bis(mesitylenesulfonyl)-N⁴-ethyl-1,4-diaminobutane

3,8,14-Tris(mesitylenesulfonyl)-3,8,14-Triazahexadecane