ACETAMIDE (15N)

Base Information

• Chemical Name: ACETAMIDE (15N)
• CAS No.: 1449-72-5
• Molecular Formula: C₂H₅NO
• Molecular Weight: 60.0611
• Mol file: 1449-72-5.mol

Synonyms:Acetamide-15N(7CI)

Chemical Property of ACETAMIDE (15N)

Chemical Property:

• Melting Point: 78-80 °C(lit.)
• Refractive Index: 1.392
• Boiling Point: 221 °C(lit.)
• PSA: 43.09000
• Density: 0.947g/cm³
• LogP: 0.19190
• Storage Temp.: Room Temperature
• Solubility.: Chloroforn (Sparingly, Sonicated), Methanol (Slightly)

Purity/Quality:

98.5% ^*data from raw suppliers

Acetamide(15N) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 40
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ACETAMIDE (15N)

There total 2 articles about ACETAMIDE (15N) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,2-trifluoroethyl acetate (406-95-1) → 15N-acetamide (1449-72-5)

Guidance literature:

With [¹⁵N]-ammonium hydroxide; at 0 - 20 ℃; for 116h;

DOI:10.1002/anie.201602054

Reference yield:

→ 15N-acetamide (1449-72-5)

Guidance literature:

aus ¹⁵NH4Cl und 1.) NaOH (->NH3); 2.) Eg./wfr.Ae.; 3.) Δ mit CH3COOH;

Reference yield: 45.0%

15N-acetamide (1449-72-5) + bis(1-methyl-1-phenylethyl)peroxide (80-43-3) → 15N-Methylacetamid (31685-41-3)

Guidance literature:

With copper(l) chloride; In chlorobenzene; for 15h; Schlenk technique; Inert atmosphere; Reflux;

DOI:10.1002/anie.201602054

upstream raw materials:

2,2,2-trifluoroethyl acetate

Downstream raw materials:

15N-Methylacetamid