1-azido-2,5-dichlorobenzene

Base Information

• Chemical Name: 1-azido-2,5-dichlorobenzene
• CAS No.: 75458-15-0
• Molecular Formula: C₆H₃Cl₂N₃
• Molecular Weight: 188.016
• Mol file: 75458-15-0.mol

Synonyms:1-azido-2,5-dichlorobenzene

Chemical Property of 1-azido-2,5-dichlorobenzene

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-azido-2,5-dichlorobenzene

There total 8 articles about 1-azido-2,5-dichlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,5-dichlorobenzeneboronic acid (135145-90-3) → 1-azido-2,5-dichlorobenzene (75458-15-0)

Guidance literature:

With copper(I) oxide; ammonium hydroxide; sodium azide; oxygen; In water; at 25 ℃; for 24h;

DOI:10.1002/chem.201003711

Reference yield:

2-azido-4-chlorobenzenamine (17537-17-6) → 1-azido-2,5-dichlorobenzene (75458-15-0)

Guidance literature:

With hydrogenchloride; water; sodium nitrite; Yield given. Multistep reaction;

DOI:10.1021/jo01314a002

Reference yield:

5-Chlor-2-phthalimidoazidobenzene (75458-18-3) → 1-azido-2,5-dichlorobenzene (75458-15-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 23 percent / NH₂NH₂*H₂O

2: 1.) NaNO₂, HCl, H₂O, 2.) CuCl₂^-

With hydrogenchloride; water; hydrazine hydrate; sodium nitrite;

DOI:10.1021/jo01314a002

upstream raw materials:

2-azido-4-chlorobenzenamine

5-Choro-2-phthalimidoaniline

5-Chloro-2-phthalimidonitrobenzene

5-Chlor-2-phthalimidoazidobenzene