Technology Process of dl-menthyl α-deuteriodiazoacetate
There total 3 articles about dl-menthyl α-deuteriodiazoacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
deuteriated sodium hydroxide; cetyldimethylbenzylammonium chloride;
In
dichloromethane; water-d2;
for 48h;
DOI:10.1021/ja00369a036
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) p-toluenesulfonic acid monohydrate, 2.) hydrogen chloride / 1.) benzene, reflux, 2.) ether
2: 1.) acetic acid, 2.) isoamyl nitrite / 2.) benzene, reflux, 6 h
3: 84 percent / sodium deuteroxide, benzylhexadecyldimethylammonium chloride / CH2Cl2; D2O / 48 h
With
hydrogenchloride; deuteriated sodium hydroxide; cetyldimethylbenzylammonium chloride; toluene-4-sulfonic acid; acetic acid; isopentyl nitrite;
In
dichloromethane; water-d2;
DOI:10.1021/ja00369a036
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) acetic acid, 2.) isoamyl nitrite / 2.) benzene, reflux, 6 h
2: 84 percent / sodium deuteroxide, benzylhexadecyldimethylammonium chloride / CH2Cl2; D2O / 48 h
With
deuteriated sodium hydroxide; cetyldimethylbenzylammonium chloride; acetic acid; isopentyl nitrite;
In
dichloromethane; water-d2;
DOI:10.1021/ja00369a036
