(3R,4R)-3-hydroxy-4-(4-methylphenyl)sulfonylamino-4-phenylbutanenitrile

Base Information

Chemical Name:(3R,4R)-3-hydroxy-4-(4-methylphenyl)sulfonylamino-4-phenylbutanenitrile
CAS No.:171358-28-4
Molecular Formula:C₁₇H₁₈N₂O₃S
Molecular Weight:330.408
Hs Code.:

Synonyms:(3R,4R)-3-hydroxy-4-(4-methylphenyl)sulfonylamino-4-phenylbutanenitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3R,4R)-3-hydroxy-4-(4-methylphenyl)sulfonylamino-4-phenylbutanenitrile

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Technology Process of (3R,4R)-3-hydroxy-4-(4-methylphenyl)sulfonylamino-4-phenylbutanenitrile

There total 2 articles about (3R,4R)-3-hydroxy-4-(4-methylphenyl)sulfonylamino-4-phenylbutanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-((1R,2R)-3-Cyano-1-phenyl-2-trimethylsilanyloxy-propyl)-4-methyl-benzenesulfonamide

: 171358-28-4
(3R,4R)-3-hydroxy-4-(4-methylphenyl)sulfonylamino-4-phenylbutanenitrile

Guidance literature:: With tetrabutyl ammonium fluoride; Yield given;
DOI:10.1016/0040-4039(95)01203-T

Reference yield:

: 7677-24-9
trimethylsilyl cyanide

: 167029-47-2
(2R,3R)-2-hydroxymethyl-1-(4-methylphenylsulfonyl)-3-phenylaziridine

: 171358-28-4
(3R,4R)-3-hydroxy-4-(4-methylphenyl)sulfonylamino-4-phenylbutanenitrile

Guidance literature:: With ytterbium cyanide; tetrabutyl ammonium fluoride; potassium hydride; Yield given. Multistep reaction;
DOI:10.1016/0040-4020(96)00682-5