dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate

Base Information

• Chemical Name: dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate
• CAS No.: 883550-71-8
• Molecular Formula: C₁₉H₂₂O₆S
• Molecular Weight: 378.446
• Mol file: 883550-71-8.mol

Synonyms:dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate

Chemical Property of dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate

There total 2 articles about dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

dimethyl 2-allyl-2-(4-hydroxypent-2-ynyl)malonate + benzenesulfenyl chloride (931-59-9) → dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate (883550-71-8)

Guidance literature:

dimethyl 2-allyl-2-(4-hydroxypent-2-ynyl)malonate; benzenesulfenyl chloride; With triethylamine; In tetrahydrofuran; at -78 ℃; for 1.5h;

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/ol0600990

Reference yield:

dimethyl allylpropargylmalonate (107428-06-8) → dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate (883550-71-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: LDA / tetrahydrofuran / -78 °C

1.2: tetrahydrofuran / -78 °C

2.1: Et₃N / tetrahydrofuran / -78 °C

2.2: mCPBA / CH₂Cl₂ / 0 °C

With triethylamine; lithium diisopropyl amide; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2006.04.017

Reference yield: 41.0%

dimethyl 2-[2-(phenylsulfonyl)penta-2,3-dienyl]-2-(2-propenyl)malonate (883550-71-8) → 3-benzenesulfonyl-5-methyl-4-vinyl-cyclohex-3-ene-1,1-dicarboxylic acid dimethyl ester

Guidance literature:

tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; for 3.5h; Heating;

DOI:10.1016/j.tetlet.2006.04.017

upstream raw materials:

benzenesulfenyl chloride

dimethyl allylpropargylmalonate