7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester

Base Information

Chemical Name:7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester
CAS No.:81424-58-0
Molecular Formula:C₃₂H₄₈O₅
Molecular Weight:512.73
Hs Code.:

Synonyms:7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester

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Chemical Property of 7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester

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Technology Process of 7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester

There total 4 articles about 7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 81424-57-9
(Z)-7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-hept-5-enoic acid methyl ester

: 81424-58-0
7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester

Guidance literature:: With hydrogen;
DOI:10.1021/jo00134a011

Reference yield:

: 13345-50-1
prostaglandin A₂

: 81424-58-0
7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / CH₂N₂ / diethyl ether

2: 78 percent

3: 73 percent / CuI

4: 100 percent / H₂

With diazomethane; copper(l) iodide; hydrogen; In diethyl ether;
DOI:10.1021/jo00134a011

Reference yield:

: 31753-19-2
(5Z,13E)-15-hydroxy-9-oxoprosta 5,10,13 trien-1-oic acid

: 81424-58-0
7-{(1R,2S,3R)-5-Oxo-3-phenyl-2-[(E)-(S)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-heptanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent

2: 73 percent / CuI

3: 100 percent / H₂

With copper(l) iodide; hydrogen;
DOI:10.1021/jo00134a011