Didansyl-L-lysine

Base Information

• Chemical Name: Didansyl-L-lysine
• CAS No.: 1263-03-2
• Molecular Formula: C₃₀H₃₆N₄O₆S₂
• Molecular Weight: 612.771
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID50431769
• Wikidata: Q82245725
• Mol file: 1263-03-2.mol

Synonyms:Didansyl-L-lysine;1263-03-2;(2S)-2,6-bis[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]hexanoic acid;n,n'-didansyl-l-lysine;SCHEMBL4146037;DTXSID50431769

Chemical Property of Didansyl-L-lysine

Chemical Property:

• Boiling Point: 809.5±75.0 °C(Predicted)
• PKA: 3.27±0.21(Predicted)
• PSA: 152.88000
• Density: 1.341±0.06 g/cm3(Predicted)
• LogP: 6.94870
• Storage Temp.: −20°C
• XLogP3: 5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 13
• Exact Mass: 612.20762723
• Heavy Atom Count: 42
• Complexity: 1100

Purity/Quality:

99% ^*data from raw suppliers

DIDANSYL-L-LYSINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NCCCCC(C(=O)O)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C
• Isomeric SMILES: CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NCCCC[C@@H](C(=O)O)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C

Technology Process of Didansyl-L-lysine

There total 1 articles about Didansyl-L-lysine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(dimethylamino)naphth-1-ylsulfonyl chloride (605-65-2) + N-2,N-6-bis(9-fluorenylmethyloxycarbonyl)-L-lysine (75932-02-4,78081-87-5) → didansyllysine (1263-03-2)

Guidance literature:

N-2,N-6-bis(9-fluorenylmethyloxycarbonyl)-L-lysine; With N-ethyl-N,N-diisopropylamine; solid phase reaction;

With piperidine; In N,N-dimethyl-formamide; solid phase reaction;

5-(dimethylamino)naphth-1-ylsulfonyl chloride; Further stages;

DOI:10.1016/j.tet.2011.03.106

upstream raw materials:

5-(dimethylamino)naphth-1-ylsulfonyl chloride

N-2,N-6-bis(9-fluorenylmethyloxycarbonyl)-L-lysine