(5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one

Base Information

Chemical Name:(5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS No.:34709-44-9
Molecular Formula:C10H7 N O2 S2
Molecular Weight:237.303
Hs Code.:
European Community (EC) Number:688-654-9
NSC Number:31202
DSSTox Substance ID:DTXSID00361522
Nikkaji Number:J1.384.177B
Wikidata:Q76119972
ChEMBL ID:CHEMBL431550
Mol file:34709-44-9.mol

Synonyms:(Z)-5-(2'-hydroxybenzylidene)-2-thioxothiazolidin-4-one;Rhod-o-hp

Suppliers and Price of (5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.56g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:236.99182081
Heavy Atom Count:15
Complexity:327

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C=C2C(=O)NC(=S)S2)O
Isomeric SMILES:C1=CC=C(C(=C1)/C=C\2/C(=O)NC(=S)S2)O

Technology Process of (5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one

There total 2 articles about (5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 141-84-4
2-thioxo-4-thiazolidinone

: 90-02-8
salicylaldehyde

: 34709-44-9
E,Z-5-(2-hydroxyphenylmethylene)-4-oxo-2-thioxo-1,3-thiazolidine

Guidance literature:: With 2?hydroxyethylammonium formate; at 20 ℃; for 0.1h; neat (no solvent);
DOI:10.1139/V10-011

Reference yield: 71.0%

: 141-84-4
2-thioxo-4-thiazolidinone

: 89-95-2
2-methyl-benzyl alcohol

: 34709-44-9
E,Z-5-(2-hydroxyphenylmethylene)-4-oxo-2-thioxo-1,3-thiazolidine

Guidance literature:: With sodium acetate; acetic acid; for 0.25h; microwave irradiation;
DOI:10.1080/00397910600941166

Reference yield: 83.0%

: 25507-25-9
[4-(4-amino-benzyl)-phenyl]-(7-chloro-quinolin-4-yl)-amine

: 34709-44-9
E,Z-5-(2-hydroxyphenylmethylene)-4-oxo-2-thioxo-1,3-thiazolidine

: C₃₂H₂₂ClN₅O₂S₂

Guidance literature:: [4-(4-amino-benzyl)-phenyl]-(7-chloro-quinolin-4-yl)-amine; With hydrogenchloride; In water; at 0 - 5 ℃;

With sodium nitrite; In water; at 0 - 5 ℃; for 0.5h; Cooling with ice;

E,Z-5-(2-hydroxyphenylmethylene)-4-oxo-2-thioxo-1,3-thiazolidine; With sodium carbonate; In ethanol; water; at 0 - 5 ℃; for 2h; Cooling with ice;
DOI:10.1007/s13738-021-02294-w