16B-HYDROXYESTRONE DIACETATE

Base Information

• Chemical Name: 16B-HYDROXYESTRONE DIACETATE
• CAS No.: 1247-70-7
• Molecular Formula: C22H26 O5
• Molecular Weight: 370.445
• Mol file: 1247-70-7.mol

Synonyms:Estra-1,3,5(10)-trien-17-one,3,16b-dihydroxy-, diacetate(6CI,7CI,8CI); 16b-Hydroxyestronediacetate

Chemical Property of 16B-HYDROXYESTRONE DIACETATE

Chemical Property:

• PSA: 69.67000
• LogP: 3.57870

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 16B-HYDROXYESTRONE DIACETATE

There total 5 articles about 16B-HYDROXYESTRONE DIACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

estra-1,3,5(10),16-tetraene-3,17-diol diacetate (20592-42-1) + acetic anhydride (108-24-7) → 3,16β-diacetoxyestra-1,3,5(10)-trien-17-one (1247-70-7) + 3-acetoxy-16β-(acetoxy)acetoxyestra-1,3,5(10)-trien-17-one

Guidance literature:

With lead(IV) acetate; acetic acid; at 20 ℃;

DOI:10.1016/S0039-128X(01)00103-9

Reference yield:

→ 16α-hydroxyestrone diacetate (1247-70-7,1247-71-8,34990-89-1,97232-24-1)

Guidance literature:

3,16α-Diacetoxy-oestratrien-(1,3,5(10))-ol-(17β), Chromsaeure, wss. Aceton;

DOI:10.1021/ja01508a043

Reference yield:

estra-1,3,5(10),16-tetraene-3,17-diol diacetate (20592-42-1) → 3,16β-diacetoxyestra-1,3,5(10)-trien-17-one (1247-70-7)

Guidance literature:

With lead(IV) acetate; acetic anhydride; acetic acid;

DOI:10.1021/jo01361a025

upstream raw materials:

estra-1,3,5⁽¹⁰⁾,16-tetraene-3,17-diol diacetate

16beta-Hydroxyestrone

acetic anhydride

Downstream raw materials:

epiestriol

16beta-Hydroxyestrone