2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

Base Information

Chemical Name:2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline
CAS No.:1250257-28-3
Molecular Formula:C₂₁H₁₇F₃N₂
Molecular Weight:354.375
Hs Code.:

Synonyms:2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

Suppliers and Price of 2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

There total 2 articles about 2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1250257-16-9
C₂₀H₁₈N₂

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 1250257-28-3
2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: C₂₀H₁₈N₂; (trifluoromethyl)trimethylsilane; With potassium fluoride; dibenzoyl peroxide; In dichloromethane; at 0 ℃; Inert atmosphere; Reflux;

With palladium 10% on activated carbon; hydrogen; In methanol; at 23 ℃; for 24h;
DOI:10.1039/c0cc01073a

Reference yield:

: 1250257-16-9
C₂₀H₁₈N₂

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 1250257-44-3
C₂₁H₁₅F₃N₂

: 1250257-28-3
2-phenyl-7-(pyridin-2-yl)-1-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: With potassium fluoride; dibenzoyl peroxide; In dichloromethane; at 0 ℃; Inert atmosphere; Reflux;
DOI:10.1039/c0cc01073a