Bendazol hydrochloride

Base Information

• Chemical Name: Bendazol hydrochloride
• CAS No.: 1212-48-2
• Molecular Formula: C14H12 N2 . Cl H
• Molecular Weight: 244.724
• Hs Code.: 2933990090
• European Community (EC) Number: 214-921-2
• UNII: ME751TL810
• DSSTox Substance ID: DTXSID30153179
• Wikidata: Q27283951
• Mol file: 1212-48-2.mol

Synonyms:1212-48-2;Bendazol hydrochloride;2-Benzyl-1H-benzo[d]imidazole hydrochloride;2-Benzylbenzimidazole Hydrochloride;Bendazol HCl;Dibazolum;2-benzyl-1H-benzimidazole;hydrochloride;2-Benzyl-1H-benzimidazole monohydrochloride;2-benzyl-1H-benzimidazole hydrochloride;UNII-ME751TL810;ME751TL810;EINECS 214-921-2;MFCD00443659;2-benzyl-1H-1,3-benzodiazole hydrochloride;2-benzyl-1H-benzimidazole,hydrochloride;DIBAZOL HYDROCHLORIDE;DIBAZOLE HYDROCHLORIDE;SCHEMBL15015931;DTXSID30153179;BENDAZOL HYDROCHLORIDE [MI];BAA21248;AKOS015909256;BENDAZOL HYDROCHLORIDE [WHO-DD];AS-65840;2-Benzyl-1H-benzo[d]imidazolehydrochloride;B4341;CS-0137965;2-Benzyl-1H-benzimidazole hydrochloride, 95%;D89068;2-BENZYL-1H-BENZOIMIDAZOLE, HYDROCHLORIDE;A909630;Q27283951;2-(phenylmethyl)-1H-Benzimidazole hydrochloride (1:1);1H-BENZIMIDAZOLE, 2-(PHENYLMETHYL)-, HYDROCHLORIDE (1:1)

Chemical Property of Bendazol hydrochloride

Chemical Property:

• Vapor Pressure: 5.52E-08mmHg at 25°C
• Melting Point: 172-175℃
• Boiling Point: 453.5oC at 760 mmHg
• Flash Point: 252.1oC
• PSA: 28.68000
• LogP: 3.95570
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: soluble in Methanol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 244.0767261
• Heavy Atom Count: 17
• Complexity: 223

Purity/Quality:

99% ^*data from raw suppliers

2-Benzylbenzimidazole Hydrochloride >98.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC2=NC3=CC=CC=C3N2.Cl

Technology Process of Bendazol hydrochloride

There total 2 articles about Bendazol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.4%

phenylacetonitrile (140-29-4) + 1,2-diamino-benzene (95-54-5) → 2-benzylbenzimidazole hydrochloride (1212-48-2)

Guidance literature:

With hydrogenchloride; In water; for 3.5h; Further Variations:; reaction time, effect of microwave activation; Product distribution; Heating;

Reference yield: 83.5%

1,2-diamino-benzene (95-54-5) + phenylacetyl chloride (103-80-0) → 2-benzylbenzimidazole hydrochloride (1212-48-2)

Guidance literature:

In toluene; at 100 - 120 ℃; for 4h; Concentration;

Reference yield:

cobalt(II) acetate (71-48-7,917-69-1,5931-89-5,55881-15-7,68931-68-0,68931-69-1,93029-27-7) + 2-benzylbenzimidazole hydrochloride (1212-48-2) → bis(2-benzylbenzimidazole)cobalt(II) chloride

Guidance literature:

In not given; elem. anal.;

upstream raw materials:

phenylacetonitrile

1,2-diamino-benzene

phenylacetyl chloride

Refernces

• 1、 El'tsov,Sokolova,Dmitrieva,Grigor'ev,Ivanov. "Synthesis of nitrogenous heterocycles under microwave activation". . p. 1317 - 1320. Retrieved 2007/10/03.