5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoic acid

Base Information

Chemical Name:5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoic acid
CAS No.:1123191-85-4
Molecular Formula:C₂₈H₃₃FO₃Si
Molecular Weight:464.652
Hs Code.:

Synonyms:5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoic acid

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Chemical Property of 5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoic acid

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Technology Process of 5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoic acid

There total 1 articles about 5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1123191-84-3
3-(tert-butyldiphenylsilanyloxy)-1-methylpropyl toluene-4-sulfonate

: 405-50-5
p-Fluorophenylacetic acid

: 1123191-85-4
5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoic acid

Guidance literature:: p-Fluorophenylacetic acid; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.833333h;

3-(tert-butyldiphenylsilanyloxy)-1-methylpropyl toluene-4-sulfonate; In tetrahydrofuran; hexane; at 20 ℃; for 12h;

Reference yield:

: 870-46-2
t-butoxycarbonylhydrazine

: 1123191-85-4
5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoic acid

: 1123191-86-5
tert-butyl N'-[5-(tert-butyldiphenylsilanyloxy)-2-(4-fluorophenyl)-3-methylpentanoyl]hydrazinecarboxylate

Guidance literature:: With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 15h;