3-Methyl-4-nitro-isothiazole

Base Information

• Chemical Name: 3-Methyl-4-nitro-isothiazole
• CAS No.: 1073-18-3
• Molecular Formula: C₄H₄N₂O₂S
• Molecular Weight: 144.154
• Hs Code.: 2934999090
• Mol file: 1073-18-3.mol

Synonyms:3-Methyl-4-nitroisothiazole

Chemical Property of 3-Methyl-4-nitro-isothiazole

Chemical Property:

• PSA: 86.95000
• LogP: 1.88290

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Methyl-4-nitro-isothiazole 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methyl-4-nitro-isothiazole

There total 3 articles about 3-Methyl-4-nitro-isothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-methyl-4-nitro-5-isothiazolecarboxylic acid (4592-53-4) → 3-Methyl-4-nitro-isothiazol (1073-18-3)

Guidance literature:

at 120 - 130 ℃; Pyrolysis;

DOI:10.1016/j.molstruc.2019.06.028

Reference yield:

3-methylisothiazole (693-92-5) → 3-Methyl-4-nitro-isothiazol (1073-18-3)

Guidance literature:

With sulfuric acid; sulfur trioxide; potassium nitrate;

DOI:10.1039/jr9590003061

Reference yield:

→ 3-Methyl-4-nitro-isothiazol (1073-18-3)

Guidance literature:

3-Methylisothiazol + konz.HNO3/H2SO4;

upstream raw materials:

3-methylisothiazole

3-methyl-4-nitro-5-isothiazolecarboxylic acid

Downstream raw materials:

3-methylisothiazol-4-amine

Refernces