Pyrimidine-2-carbohydrazonamide

Base Information

• Chemical Name: Pyrimidine-2-carbohydrazonamide
• CAS No.: 1005-03-4
• Molecular Formula: C5H7 N5
• Molecular Weight: 137.14258
• DSSTox Substance ID: DTXSID40707526
• Mol file: 1005-03-4.mol

Synonyms:Pyrimidine-2-carbohydrazonamide;1005-03-4;DTXSID40707526;HXNCJZYYCKSCAK-UHFFFAOYSA-N;N-Amino-pyrimidine-2-carboxamidine;AKOS010600759

Chemical Property of Pyrimidine-2-carbohydrazonamide

Chemical Property:

• PSA: 90.18000
• LogP: 0.45620
• Storage Temp.: 2-8°C
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 137.07014524
• Heavy Atom Count: 10
• Complexity: 126

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pyrimidine-2-carboximidhydrazide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(N=C1)C(=NN)N

Technology Process of Pyrimidine-2-carbohydrazonamide

There total 3 articles about Pyrimidine-2-carbohydrazonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-cyanopyrimidine (14080-23-0) → pyrimidine-2-carboximidohydrazide (1005-03-4)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2016.07.052

Reference yield: 90.0%

2-cyanopyrimidine (14080-23-0) → pyrimidine-2-carbamidrazone (1005-03-4)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1007/s11172-010-0317-7

Reference yield:

→ pyrimidine-2-carboximidohydrazide (1005-03-4)

Guidance literature:

2-Cyan-pyrimidin, 95percent N2H4, EtOH (RT, 2h);

DOI:10.1021/jo01014a502

upstream raw materials:

2-cyanopyrimidine

Downstream raw materials:

5,6-bis(4-bromophenyl)-3-(pyrimidin-2-yl)-1,2,4-triazine

Refernces

• 1、 Krivopalov,Bushuev,Gatilov,Shkurko. "Synthesis of symmetrical di(pyrimidin-2-yl)-1,2,4-triazoles and di(pyrimidin-2-yl)-1,2,4,5-tetrazines". . p. 1808 - 1816. Retrieved 2010.