t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate

Base Information

Chemical Name:t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate
CAS No.:544703-53-9
Molecular Formula:C₃₉H₄₉NO₁₃Si
Molecular Weight:767.902
Hs Code.:

Synonyms:t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate

Suppliers and Price of t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate

There total 9 articles about t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 544703-52-8
t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

: 544703-53-9
t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane;
DOI:10.1016/S0040-4039(03)00287-9

Reference yield:

: 81704-03-2
3,4,6-tri-O-acetyl-2-deoxy-2-phtalimido-α-D-galacto-pyranosyl bromide

: 544703-53-9
t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate

Guidance literature:: Multi-step reaction with 4 steps

1: 58 percent / AgOTf / CH₂Cl₂

2: 100 percent / H₂ / Pd-C / methanol; ethyl acetate

3: 95 percent / imid.; DMAP / dimethylformamide

4: 41 percent / DDQ / dioxane

With 1H-imidazole; dmap; hydrogen; silver trifluoromethanesulfonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium on activated charcoal; In 1,4-dioxane; methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(03)00287-9

Reference yield:

: 128316-64-3,481072-37-1
(+/-)-methyl 3-p-benzyloxyphenyl-2-hydroxypropionate

: 544703-53-9
t-butyl (Z)-2-(3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenyl-2-acrylate

Guidance literature:: Multi-step reaction with 8 steps

1: KOH / methanol; H₂O

2: 100 percent / pyr

3: 78 percent / DMAP; DCC / CH₂Cl₂

4: 98 percent / NaOMe / methanol

5: 58 percent / AgOTf / CH₂Cl₂

6: 100 percent / H₂ / Pd-C / methanol; ethyl acetate

7: 95 percent / imid.; DMAP / dimethylformamide

8: 41 percent / DDQ / dioxane

With pyridine; 1H-imidazole; dmap; potassium hydroxide; hydrogen; sodium methylate; silver trifluoromethanesulfonate; dicyclohexyl-carbodiimide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium on activated charcoal; In 1,4-dioxane; methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(03)00287-9