t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

Base Information

Chemical Name:t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate
CAS No.:544703-52-8
Molecular Formula:C₃₉H₅₁NO₁₃Si
Molecular Weight:769.918
Hs Code.:

Synonyms:t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

Suppliers and Price of t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

There total 8 articles about t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 2-[(2S,3R,4R,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-tetrahydro-pyran-2-yloxy]-3-(4-hydroxy-phenyl)-propionic acid tert-butyl ester

: 544703-52-8
t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

Guidance literature:: With 1H-imidazole; dmap; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(03)00287-9

Reference yield:

: 81704-03-2
3,4,6-tri-O-acetyl-2-deoxy-2-phtalimido-α-D-galacto-pyranosyl bromide

: 544703-52-8
t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

Guidance literature:: Multi-step reaction with 3 steps

1: 58 percent / AgOTf / CH₂Cl₂

2: 100 percent / H₂ / Pd-C / methanol; ethyl acetate

3: 95 percent / imid.; DMAP / dimethylformamide

With 1H-imidazole; dmap; hydrogen; silver trifluoromethanesulfonate; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(03)00287-9

Reference yield:

: 128316-64-3,481072-37-1
(+/-)-methyl 3-p-benzyloxyphenyl-2-hydroxypropionate

: 544703-52-8
t-butyl (3',4',6'-tri-O-acetyl-2'-deoxy-2'-phthalimido-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsilyloxyphenylpropionate

Guidance literature:: Multi-step reaction with 7 steps

1: KOH / methanol; H₂O

2: 100 percent / pyr

3: 78 percent / DMAP; DCC / CH₂Cl₂

4: 98 percent / NaOMe / methanol

5: 58 percent / AgOTf / CH₂Cl₂

6: 100 percent / H₂ / Pd-C / methanol; ethyl acetate

7: 95 percent / imid.; DMAP / dimethylformamide

With pyridine; 1H-imidazole; dmap; potassium hydroxide; hydrogen; sodium methylate; silver trifluoromethanesulfonate; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(03)00287-9