N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine

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Chemical Name:N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine
CAS No.:1035943-89-5
Molecular Formula:C₁₈H₁₉ClN₆
Molecular Weight:354.842
Hs Code.:

Synonyms:N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine

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Chemical Property of N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine

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Technology Process of N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine

There total 3 articles about N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1035943-65-7
(3-chloro-phenyl)-[4-(2-chloro-pyridin-3-yl)-pyrimidin-2-yl]-amine

: 109-76-2,54018-94-9
Trimethylenediamine

: 1035943-89-5
N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine

Guidance literature:: at 110 ℃; for 0.5h; Sealed tube;

Reference yield:

: 381248-04-0
(2-chloropyridin-3-yl)boronic acid

: 1035943-89-5
N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 14 h / 95 °C

2: toluene-4-sulfonic acid / 1,4-dioxane / 1.5 h / 110 °C / Sealed tube

3: 0.5 h / 110 °C / Sealed tube

With sodium carbonate; toluene-4-sulfonic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water;

Reference yield:

: 870221-39-9
2-chloro-4-(2-chloro-pyridin-3-yl)-pyrimidine

: 1035943-89-5
N-{3-[2-(3-chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propane-1,3-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / 1,4-dioxane / 1.5 h / 110 °C / Sealed tube

2: 0.5 h / 110 °C / Sealed tube

With toluene-4-sulfonic acid; In 1,4-dioxane;