2,2',3,3',5,5',6,6'-OCTAFLUORO-4,4'-BIPHENYLDICARBONITRILE

Base Information

• Chemical Name: 2,2',3,3',5,5',6,6'-OCTAFLUORO-4,4'-BIPHENYLDICARBONITRILE
• CAS No.: 28442-30-0
• Molecular Formula: C14F8 N2
• Molecular Weight: 348.155
• Hs Code.: 2926909090
• Mol file: 28442-30-0.mol

Synonyms:4,4'-Biphenyldicarbonitrile,2,2',3,3',5,5',6,6'-octafluoro- (8CI); 2,2',3,3',5,5',6,6'-Octafluoro-4,4'-biphenyldinitrile;4,4'-Dicyanooctafluorobiphenyl

Chemical Property of 2,2',3,3',5,5',6,6'-OCTAFLUORO-4,4'-BIPHENYLDICARBONITRILE

Chemical Property:

• Melting Point: 132-134 °C(lit.)
• PSA: 47.58000
• LogP: 4.20976

Purity/Quality:

99% ^*data from raw suppliers

2,2',3,3',5,5',6,6'-OCTAFLUORO-4,4'-BIPHENYLDICARBONITRILE 98.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2',3,3',5,5',6,6'-OCTAFLUORO-4,4'-BIPHENYLDICARBONITRILE

There total 6 articles about 2,2',3,3',5,5',6,6'-OCTAFLUORO-4,4'-BIPHENYLDICARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

4-iodo-2,3,5,6-tetrafluoro-benzonitrile (31469-85-9) + 2,3,5,6-tetrafluorobenzonitrile (5216-17-1) → 1,1’-(dicyano)-2,2’,3,3’,5,5’,6,6’-octafluoro-4,4’-biphenyl (28442-30-0)

Guidance literature:

With potassium phosphate; copper(l) iodide; 1,10-Phenanthroline; In 1,4-dioxane; at 125 ℃; for 12h; Inert atmosphere; Glovebox;

DOI:10.1039/c3cc41564c

Reference yield: 60.0%

Pentafluorobenzonitrile (773-82-0) → 1,1’-(dicyano)-2,2’,3,3’,5,5’,6,6’-octafluoro-4,4’-biphenyl (28442-30-0)

Guidance literature:

With hexaethylphosphoric triamide; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1055/a-1470-6050

Reference yield: 38.0%

4-Bromo-2,3,5,6-tetrafluorobenzonitrile (17823-40-4) → 1,1’-(dicyano)-2,2’,3,3’,5,5’,6,6’-octafluoro-4,4’-biphenyl (28442-30-0)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 - 25 ℃; for 5h; Inert atmosphere;

upstream raw materials:

2,3,4,5,6-Pentafluoro-benzonitrile

2,3,5,6,2',3',5',6'-Octafluoro-biphenyl-4,4'-dicarboxylic acid diamide

Pentafluorobenzonitrile

4-iodo-2,3,5,6-tetrafluoro-benzonitrile

Downstream raw materials:

5,5'-(perfluorobiphenyl-4,4'-diyl)bis(1H-tetrazole)

2,2',3,3',5,5',6,6'-octafluoro-[1,1'-biphenyl]-4,4'-dicarboxylic acid

Refernces

• 1、 Wang, Guangbo,Leus, Karen,Jena, Himanshu Sekhar,Krishnaraj, Chidharth,Zhao, Shuna,Depauw, Hannes,Tahir, Norini,Liu, Ying-Ya,Van Der Voort, Pascal. "A fluorine-containing hydrophobic covalent triazine framework with excellent selective CO2 capture performance". . p. 6370 - 6375. Retrieved 2018.
• 2、 Taylor, Rupert G. D.,Bezzu, C. Grazia,Carta, Mariolino,Msayib, Kadhum J.,Walker, Jonathan,Short, Rhys,Kariuki, Benson M.,McKeown, Neil B.. "The Synthesis of Organic Molecules of Intrinsic Microporosity Designed to Frustrate Efficient Molecular Packing". supporting information. p. 2466 - 2472. Retrieved 2016/02/18.