(2,5-Dioxopyrrolidin-1-yl) 2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]acetate

Base Information

Chemical Name:(2,5-Dioxopyrrolidin-1-yl) 2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]acetate
CAS No.:23446-04-0
Molecular Formula:C₁₆H₂₅N₃O₇S
Molecular Weight:403.456
Hs Code.:
DSSTox Substance ID:DTXSID401126922
Mol file:23446-04-0.mol

Synonyms:Boc-Met-Gly-OSu;23446-04-0;(2,5-Dioxopyrrolidin-1-yl) 2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]acetate;DTXSID401126922;2,5-Pyrrolidinedione, 1-[[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-methionyl]glycyl]oxy]-;(S)-2,5-dioxopyrrolidin-1-yl 2-(2-(tert-butoxycarbonylamino)-4-(methylthio)butanamido)acetate

Suppliers and Price of (2,5-Dioxopyrrolidin-1-yl) 2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
BOC-MET-GLY-OSU
50mg
$ 45.00

Biosynth Carbosynth
Boc-Met-Gly-OSu
25 g
$ 1350.00

Biosynth Carbosynth
Boc-Met-Gly-OSu
10 g
$ 621.00

Biosynth Carbosynth
Boc-Met-Gly-OSu
5 g
$ 365.00

Biosynth Carbosynth
Boc-Met-Gly-OSu
2 g
$ 183.00

Biosynth Carbosynth
Boc-Met-Gly-OSu
1 g
$ 105.00

Abosyn
Boc-Met-Gly-Osu 95%-98%
1g
$ 75.00

Total 6 raw suppliers

Chemical Property of (2,5-Dioxopyrrolidin-1-yl) 2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]acetate

Chemical Property:

PKA:11.06±0.46(Predicted)
PSA：156.41000
Density:1.31±0.1 g/cm3(Predicted)
LogP:1.07590
Storage Temp.:-15°C
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:11
Exact Mass:403.14132132
Heavy Atom Count:27
Complexity:587

Purity/Quality:

99% ^*data from raw suppliers

BOC-MET-GLY-OSU ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CCSC)C(=O)NCC(=O)ON1C(=O)CCC1=O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CCSC)C(=O)NCC(=O)ON1C(=O)CCC1=O

Technology Process of (2,5-Dioxopyrrolidin-1-yl) 2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]acetate

There total 2 articles about (2,5-Dioxopyrrolidin-1-yl) 2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 23446-03-9
2-((2S)-2-((tert-butoxycarbonyl)amino)-4-(methylthio)butanamido)acetic acid

: 23446-04-0
Boc-Met-Gly-OSu

Guidance literature:: With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; Ambient temperature;
DOI:10.1021/jm00391a017

Reference yield:

: 23446-04-0
Boc-Met-Gly-OSu

Guidance literature:: Boc-Met-Gly (III), N-Hydroxysuccinimid, Dicyclohexylcarbodiimid, DMF, -10grad;

Reference yield:

: 23446-04-0
Boc-Met-Gly-OSu

: (S)-3-{(S)-2-[(S)-2-[2-((S)-2-Amino-4-methylsulfanyl-butyrylamino)-acetylamino]-3-(1H-indol-3-yl)-propionylamino]-hexanoylamino}-4-((S)-1-carbamoyl-2-phenyl-ethylamino)-butyric acid

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-diisopropylethylamine / dimethylformamide / 2 h / Ambient temperature

2: TFA / 0.5 h

With N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In N,N-dimethyl-formamide;
DOI:10.1021/jm00391a017