4-Hydroxy-8-nitroquinoline

Base Information

• Chemical Name: 4-Hydroxy-8-nitroquinoline
• CAS No.: 23432-46-4
• Molecular Formula: C₉H₆N₂O₃
• Molecular Weight: 190.158
• Hs Code.: 2933499090
• NSC Number: 149795
• DSSTox Substance ID: DTXSID50946641
• Nikkaji Number: J1.612.029D
• Wikidata: Q82924266
• ChEMBL ID: CHEMBL1078566
• Mol file: 23432-46-4.mol

Synonyms:4-HYDROXY-8-NITROQUINOLINE;23432-46-4;8-Nitroquinolin-4-ol;8-nitro-1H-quinolin-4-one;23833-95-6;8-nitroquinolin-4(1H)-one;NSC149795;8-nitro-quinolin-4-ol;8-Nitroquinoline-4(1H)-one;SCHEMBL6537493;CHEMBL1078566;DTXSID50946641;1,4-dihydro-4-oxo-8-nitroquinoline;1,4-dihydro-8-nitro-4-oxoquinoline;AKOS006289043;NSC-149795;SB67952

Chemical Property of 4-Hydroxy-8-nitroquinoline

Chemical Property:

• PSA: 78.94000
• LogP: 2.37180
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 190.03784206
• Heavy Atom Count: 14
• Complexity: 295

Purity/Quality:

95% ^*data from raw suppliers

8-Nitroquinolin-4-ol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)[N+](=O)[O-])NC=CC2=O

Technology Process of 4-Hydroxy-8-nitroquinoline

There total 5 articles about 4-Hydroxy-8-nitroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

quinolin-4-ol (611-36-9) → 8-nitro-quinolin-4-ol (23432-46-4)

Guidance literature:

With sodium hydroxide; nitric acid; In sulfuric acid;

Reference yield:

→ 8-nitro-quinolin-4-ol (23432-46-4)

Guidance literature:

With diphenylether; biphenyl;

DOI:10.1021/ja01211a039

Reference yield:

4-chloro-8-nitroquinoline (23833-99-0) → 8-nitro-quinolin-4-ol (23432-46-4)

Guidance literature:

With hydrogenchloride; water;

DOI:10.1021/ja01194a044

upstream raw materials:

4-chloro-8-nitroquinoline

4-chloroquinoline

quinolin-4-ol

Downstream raw materials:

8-amino-quinolin-4-ol

4-chloro-8-nitroquinoline

4-Benzyloxy-8-nitroquinoline