2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

Base Information

Chemical Name:2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester
CAS No.:667900-57-4
Molecular Formula:C₆₅H₈₁N₉O₁₄
Molecular Weight:1212.41
Hs Code.:

2-[2-(5-<i>tert</i>-butoxycarbonylamino-2-{2-[2-[3-<i>tert</i>-butoxycarbonyl-2-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1<i>H</i>-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

Synonyms:2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

Suppliers and Price of 2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

There total 3 articles about 2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 75-65-0
tert-butyl alcohol

: 667900-56-3
2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

: 667900-57-4
2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

Guidance literature:: With dmap; 1-hydroxy-7-aza-benzotriazole; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/ejoc.200300477

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 667900-57-4
2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 82.5 percent / Et₃N; DMAP / tetrahydrofuran / 2 h / 20 °C

2: 87 percent / DCC; 1-hydroxy-7-azabenzotriazole; DMAP / tetrahydrofuran / 20 °C

With dmap; 1-hydroxy-7-aza-benzotriazole; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran;
DOI:10.1002/ejoc.200300477

Reference yield:

: 667900-55-2
(S)-2-[(R)-2-((S)-5-Amino-2-{(S)-2-[(S)-2-[(S)-3-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

: 667900-57-4
2-[2-(5-tert-butoxycarbonylamino-2-{2-[2-[3-tert-butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-3-phenyl-propionylamino]-succinamic acid allyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 82.5 percent / Et₃N; DMAP / tetrahydrofuran / 2 h / 20 °C

2: 87 percent / DCC; 1-hydroxy-7-azabenzotriazole; DMAP / tetrahydrofuran / 20 °C

With dmap; 1-hydroxy-7-aza-benzotriazole; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran;
DOI:10.1002/ejoc.200300477