1-(6-carbamoyl pyridin-3-yl)piperidin-4-yl 4-isopropylpiperazine-1-carboxylate

Base Information

• Chemical Name: 1-(6-carbamoyl pyridin-3-yl)piperidin-4-yl 4-isopropylpiperazine-1-carboxylate
• CAS No.: 1429414-20-9
• Molecular Formula: C₁₉H₂₉N₅O₃
• Molecular Weight: 375.471
• Mol file: 1429414-20-9.mol

Synonyms:1-(6-carbamoyl pyridin-3-yl)piperidin-4-yl 4-isopropylpiperazine-1-carboxylate

Chemical Property of 1-(6-carbamoyl pyridin-3-yl)piperidin-4-yl 4-isopropylpiperazine-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(6-carbamoyl pyridin-3-yl)piperidin-4-yl 4-isopropylpiperazine-1-carboxylate

There total 1 articles about 1-(6-carbamoyl pyridin-3-yl)piperidin-4-yl 4-isopropylpiperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-cyano-5-chloropyridine (89809-64-3) → 1-(6-carbamoyl pyridin-3-yl)piperidin-4-yl 4-isopropylpiperazine-1-carboxylate (1429414-20-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 3 h / 140 °C

2.1: dmap / dichloromethane / 1 h / 20 °C

2.2: 5 h / 20 °C

3.1: dihydrogen peroxide; lithium hydroxide / water / 5 h / 20 °C

With dmap; dihydrogen peroxide; tetra-(n-butyl)ammonium iodide; potassium carbonate; lithium hydroxide; In dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/cmdc.201900176

upstream raw materials:

2-cyano-5-chloropyridine