2-chloro-N-cyclohexyl-N-ethylacetamide

Base Information

• Chemical Name: 2-chloro-N-cyclohexyl-N-ethylacetamide
• CAS No.: 2567-61-5
• Molecular Formula: C10H18 Cl N O
• Molecular Weight: 203.71
• DSSTox Substance ID: DTXSID40368439
• Wikidata: Q82154977
• Mol file: 2567-61-5.mol

Synonyms:2-chloro-N-cyclohexyl-N-ethylacetamide;2567-61-5;2-chloro-N-cyclohexyl-N-ethyl-acetamide;N-ethyl-N-cyclohexyl-chloroacetamide;SCHEMBL2934325;DTXSID40368439;CUTKXXKVSDIVMV-UHFFFAOYSA-N;ADAL1186391;CAA56761;MFCD03147372;AKOS002364180;AT33081;NCGC00332875-01;AS-82655;CS-0218674;EN300-01688;AB01327223-02;Z56891379

Chemical Property of 2-chloro-N-cyclohexyl-N-ethylacetamide

Chemical Property:

• PSA: 20.31000
• LogP: 2.40640
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 203.1076919
• Heavy Atom Count: 13
• Complexity: 166

Purity/Quality:

99%min ^*data from raw suppliers

2-CHLORO-N-CYCLOHEXYL-N-ETHYL-ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(C1CCCCC1)C(=O)CCl

Technology Process of 2-chloro-N-cyclohexyl-N-ethylacetamide

There total 3 articles about 2-chloro-N-cyclohexyl-N-ethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

N-ethyl-cyclohexanamine (5459-93-8) + chloroacetyl chloride (79-04-9) → N-cyclohexyl-N-ethylchloroacetamide (2567-61-5)

Guidance literature:

With triethylamine; In benzene; for 1h; Ambient temperature;

DOI:10.1248/cpb.37.322

Reference yield:

monochloroacetic acid anhydride (4015-58-1) + N-ethyl-cyclohexanamine (5459-93-8) → N-cyclohexyl-N-ethylchloroacetamide (2567-61-5)

Guidance literature:

Reference yield:

→ N-cyclohexyl-N-ethylchloroacetamide (2567-61-5)

Guidance literature:

/BRN= 2639645/;

DOI:10.1021/ja01592a061

upstream raw materials:

monochloroacetic acid anhydride

N-ethyl-cyclohexanamine

chloroacetyl chloride

Downstream raw materials:

N-cyclohexyl-N-ethyl-2-<(1-methyl-5-tetrazolyl)thio>acetamide

Refernces

• 1、 -. "Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers". . . Retrieved 2008/06/13.