(3S,4S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-HEXANONE

Base Information

Chemical Name:(3S,4S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-HEXANONE
CAS No.:28094-25-9
Molecular Formula:C₁₅H₁₉N₃O₃
Molecular Weight:289.334
Hs Code.:
Mol file:28094-25-9.mol

Synonyms:(3S,4S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-HEXANONE;N-ALPHA-BENZYLOXYCARBONYL-L-ISOLEUCINYL-DIAZOMETHANE;Z-L-ILE-CHN2

Suppliers and Price of (3S,4S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-HEXANONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (3S,4S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-HEXANONE

Chemical Property:

PSA：80.48000
LogP:1.01246

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3S,4S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-HEXANONE

There total 11 articles about (3S,4S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-HEXANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 3160-59-6
N-Cbz-L-Isoleucine

: 114715-76-3,28094-25-9
(3-diazo-1-(S)-(1-methylpropyl)-2-oxopropyl)carbamic acid benzyl ester

Guidance literature:: N-Cbz-L-Isoleucine; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; diethyl ether; at -25 ℃; for 0.5h;

diazomethane; In tetrahydrofuran; diethyl ether; at -10 - 100 ℃; for 3h;
DOI:10.1016/j.tetasy.2005.01.049

Reference yield: 78.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 3160-59-6,4276-05-5,28862-89-7,55723-45-0,55723-48-3,127866-12-0
N-benzyloxycarbonylamino-D-alloisoleucine

: 1207973-87-2,28094-25-9
benzyl (S)-(1-diazo-4-methyl-2-oxohexan-2-yl)carbamate

Guidance literature:: N-benzyloxycarbonylamino-D-alloisoleucine; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; at -15 - 0 ℃; Inert atmosphere;

diazomethane; In tetrahydrofuran; diethyl ether; at 0 - 23 ℃; Inert atmosphere;
DOI:10.1021/ja9082842