4-Pyrimidinamine, 6-methoxy-2-methyl- (9CI)

Base Information

• Chemical Name: 4-Pyrimidinamine, 6-methoxy-2-methyl- (9CI)
• CAS No.: 23132-67-4
• Molecular Formula: C6H9 N3 O
• Molecular Weight: 139.157
• Hs Code.: 2933599090
• Mol file: 23132-67-4.mol

Synonyms:Pyrimidine,4-amino-6-methoxy-2-methyl- (8CI); 4-Amino-6-methoxy-2-methylpyrimidine

Chemical Property of 4-Pyrimidinamine, 6-methoxy-2-methyl- (9CI)

Chemical Property:

• PSA: 61.03000
• LogP: 0.95700
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

6-Methoxy-2-methyl-pyrimidin-4-ylamine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Pyrimidinamine, 6-methoxy-2-methyl- (9CI)

There total 3 articles about 4-Pyrimidinamine, 6-methoxy-2-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-amino-2-methylpyrimidin-4(3H)-one (767-16-8) → 2-methyl-4-amino-6-methoxypyrimidine (23132-67-4)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃

2: methanol

With methanol; trichlorophosphate;

Reference yield:

4-amino-6-chloro-2-methylpyrimidine (1749-68-4) + sodium methylate (124-41-4) → 2-methyl-4-amino-6-methoxypyrimidine (23132-67-4)

Guidance literature:

With methanol;

Reference yield:

→ 2-methyl-4-amino-6-methoxypyrimidine (23132-67-4)

Guidance literature:

6-Amino-4-chloro-2-methyl-pyrimidin (IV), Na-Alkolat;

upstream raw materials:

4-amino-6-chloro-2-methylpyrimidine

sodium methylate

6-amino-2-methylpyrimidin-4(3H)-one

Downstream raw materials:

4-acetylamino-N-(6-methoxy-2-methyl-pyrimidin-4-yl)-benzenesulfonamide

bis-(N-acetyl-sulfanilyl)-(6-methoxy-2-methyl-pyrimidin-4-yl)-amine

sulfametomidine

(7-methoxy-5-methylimidazo<1,2-c>pyrimidin-2-yl)phenylmethanone