Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol

Base Information

• Chemical Name: Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol
• CAS No.: 1226758-61-7
• Molecular Formula: C₇₄H₁₁₂N₁₀O₁₃
• Molecular Weight: 1349.76

Synonyms:Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol

Chemical Property of Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol

There total 1 articles about Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.5%

Nα,N',Nα,N'-tetrakis(3-aminopropyl)-L-β,ζ-diaminohexanol hydrochloride + Boc-Phe-OTcp (7535-57-1) → Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol (1226758-61-7)

Guidance literature:

Nα,N',Nα,N'-tetrakis(3-aminopropyl)-L-β,ζ-diaminohexanol hydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 40 ℃;

Boc-Phe-OTcp; In N,N-dimethyl-formamide; at 20 ℃; for 168h;

DOI:10.3390/molecules14103881

Reference yield:

Boc-Lys(2-chlorocarbobenzoxy)-OH (195869-14-8) + Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol (1226758-61-7) → C130H180Cl4N18O25

Guidance literature:

Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

Boc-Lys(2-chlorocarbobenzoxy)-OH; With 1-hydroxy-pyrrolidine-2,5-dione; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 48h;

DOI:10.3390/molecules14103881

upstream raw materials:

Boc-Phe-OTcp

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