Bis(4-fluorophenyl)chlorophosphine

Base Information

• Chemical Name: Bis(4-fluorophenyl)chlorophosphine
• CAS No.: 23039-97-6
• Molecular Formula: C12H8 Cl F2 P
• Molecular Weight: 256.619
• Hs Code.: 2903999090
• DSSTox Substance ID: DTXSID50402631
• Nikkaji Number: J3.343.180E
• Mol file: 23039-97-6.mol

Synonyms:BIS(4-FLUOROPHENYL)CHLOROPHOSPHINE;23039-97-6;Chloro-bis(4-fluorophenyl)phosphane;Chlorobis(4-fluorophenyl)phosphine;chlorobis(4-fluorophenyl)phosphane;Phosphinous chloride, P,P-bis(4-fluorophenyl)-;SCHEMBL2153517;DTXSID50402631;PYFWYPBHSZATST-UHFFFAOYSA-N;bis-(4-fluorophenyl)chlorophosphine;MFCD04972302;AKOS037646192;AS-67185;CS-0106860;FT-0745380

Chemical Property of Bis(4-fluorophenyl)chlorophosphine

Chemical Property:

• Vapor Pressure: 0.000977mmHg at 25°C
• Boiling Point: 312.3°Cat760mmHg
• Flash Point: 142.7°C
• PSA: 13.59000
• Density: g/cm³
• LogP: 3.55130
• Sensitive.: Moisture Sensitive
• Water Solubility.: Reacts with water.
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 256.0020213
• Heavy Atom Count: 16
• Complexity: 189

Purity/Quality:

98% ^*data from raw suppliers

Bis(4-fluorophenyl)chlorophosphine, min. 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1F)P(C2=CC=C(C=C2)F)Cl
• Uses: In chemical research. Used as an interphasic transfer catalyst, a polymerization catalyst, and a trans-halogenation catalyst. As a precursor to fire-retardant materials.

Technology Process of Bis(4-fluorophenyl)chlorophosphine

There total 5 articles about Bis(4-fluorophenyl)chlorophosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(4-fluorophenyl)phosphine oxide (94940-35-9) → bis-(4-fluorophenyl)chlorophosphine (23039-97-6)

Guidance literature:

With phosphorus trichloride; In dichloromethane; for 1.5h;

DOI:10.1021/ja00101a007

Reference yield:

1-Bromo-4-fluorobenzene (460-00-4) → bis-(4-fluorophenyl)chlorophosphine (23039-97-6)

Guidance literature:

1-Bromo-4-fluorobenzene; With magnesium; In tetrahydrofuran; at 20 ℃; for 2h;

With diethylphosphoramidous dichloride; In tetrahydrofuran; at 0 - 50 ℃; for 3h;

With hydrogenchloride; In pentane; at 0 ℃; for 1h;

DOI:10.1016/S0957-4166(99)00341-9

Reference yield:

C16H18F2NP (25186-18-9) → bis-(4-fluorophenyl)chlorophosphine (23039-97-6)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; cyclohexane;

DOI:10.1021/ja00101a007

upstream raw materials:

bis(4-fluorophenyl)phosphine oxide

C₁₆H₁₈F₂NP

1-Bromo-4-fluorobenzene

4-flourophenylmagnesium bromide

Downstream raw materials:

allylbis(4-fluorophenyl)phosphine

7-(di(p-fluorophenyl)phosphino)-3-(pyridin-2'-yl)-[1,2,3]triazolo[1,5-a]pyridine

3-(6'-(di(p-fluorophenyl)phosphino)pyridin-2'-yl)-[1,2,3]triazolo[1,5-a]pyridine

C₂₃H₁₅F₂N₄PSe