2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole

Base Information

• Chemical Name: 2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole
• CAS No.: 134306-68-6
• Molecular Formula: C₁₉H₁₉NOSSe
• Molecular Weight: 388.392
• Mol file: 134306-68-6.mol

Synonyms:2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole

Chemical Property of 2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole

There total 3 articles about 2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylallylmagnesium chloride (5674-01-1) + 2-(2-phenyl-2-oxoethylseleno)benzothiazole (134306-62-0) → 2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole (134306-68-6)

Guidance literature:

With boron trifluoride diethyl etherate; Yield given. Multistep reaction; 1.) THF, 0 deg C, 5 min, 2.) THF, 0 deg C, 1 h;

DOI:10.1246/bcsj.65.3163

Reference yield:

di(1,3-benzothiazole-2-yl) diselenide (4542-25-0) → 2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole (134306-68-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) NaBH₄ / 1) ethanol, 2) ethanol

2: 1) Mg, 2) BF₃*OEt₂ / 1) THF, 2) CH₂Cl₂, 0 deg C, 1h

With sodium tetrahydroborate; boron trifluoride diethyl etherate; magnesium;

Reference yield:

2-(2-phenyl-2-oxoethylseleno)benzothiazole (134306-62-0) + 3-Chloro-2-methylpropene (563-47-3) → 2-(2-hydroxy-2-phenyl-4-methyl-4-pentenylseleno)benzothiazole (134306-68-6)

Guidance literature:

With boron trifluoride diethyl etherate; magnesium; Yield given. Multistep reaction; 1) THF, 2) CH₂Cl₂, 0 deg C, 1h;

upstream raw materials:

2-methylallylmagnesium chloride

2-(2-phenyl-2-oxoethylseleno)benzothiazole

3-Chloro-2-methylpropene

di(1,3-benzothiazole-2-yl) diselenide

Downstream raw materials:

2(3H)-Benzothiazolone

(4-methylpenta-1,4-dien-2-yl)benzene

Triphenylphosphine selenide